Results 241 to 250 of about 6,047,039 (310)

Biosimilars versus biological therapy in inflammatory bowel disease: challenges and targeting strategies using drug delivery systems. [PDF]

Clin Exp Med
Aljabri A, Soliman GM, Ramadan YN, Medhat MA, Hetta HF.   +4 more
europepmc   +1 more source

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

Molecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński, Krzysztof Pastuszak, Anna Samelak‐Czajka, Zuzanna Cemka, Paulina Jackowiak, Tomasz Stefaniak, Sylwia Łapińska‐Szumczyk, Jacek Jassem, Anna J. Żaczek, Matthew T. Rondina, Myron G. Best, Sjors G. J. G. In 't Veld, Anna Supernat   +12 more
wiley   +1 more source

Relapsing Eosinophilia in a Severe Allergic Asthma Patient on Biological Therapy. [PDF]

J Clin Med
Raduna O, Oprescu B, Mihaicuta S, Frent S.   +3 more
europepmc   +1 more source

Vascular normalization confers an endothelial immune suppressive gene expression profile

Molecular Oncology, EarlyView.
We compare the immunoregulatory gene expression profiles of healthy endothelial cells or endothelial cells from tumors having a normalized endothelium (low leakage) with that of wild‐type tumors (high leakage) and observe that the wild‐type tumor endothelium exhibits immunostimulatory properties.
Liqun He, Michael Welsh
wiley   +1 more source

Diffusion-weighted imaging to predict longer-term response in Crohn's disease patients commencing biological therapy: results from the MOTILITY trial. [PDF]

Br J Radiol
Hameed M, Taylor SA, Ahmed N, Chowdhury K, Patel A, Helbren E, Bhagwanani A, Hyland R, Bhatnagar G, Sidhu H, Lambie H, Franklin J, Mohsin M, Thomson E, Boone D, Tolan D, Rahman S, Sakai NS, Moran GW, Hart A, Bloom S, Menys A, Jacobs I, Halligan S, Plumb AA, MOTILITY Trial Investigators .   +25 more
europepmc   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Macrophage-Targeting DNA Nanomaterials: A Future Direction of Biological Therapy. [PDF]

Int J Nanomedicine
Tu YC, Wang YM, Yao LJ.
europepmc   +1 more source

Cardiovascular adverse event reporting in psoriasis and psoriatic arthritis biological therapy clinical trials. [PDF]

Int J Womens Dermatol
Saha S, Ottensoser M, Weber BN, Berger JS, Garshick MS.   +4 more
europepmc   +1 more source

A retrospective study on potential drug‒drug interactions in patients with severe asthma receiving biological therapy: a single-center experience. [PDF]

BMC Pulm Med
Momcilovic M, Turcic P, Butkovic F, Grle SP.   +3 more
europepmc   +1 more source