Results 121 to 130 of about 5,433,801 (311)

Transport of Drugs Through Biological Barriers—An Asset or Risk

open access: yesPharmaceutics
Biological barriers are both cellular and enzymatic interfaces between different compartments of a living organism [...]
Anna Weronika Sobańska
doaj   +1 more source

Annual Report - Marine Biological Laboratory, 1917

open access: yes, 1918
Annual report of the Marine Biological Laboratory in Woods Hole. 1917.
Marine Biological Laboratory (Woods Hole MA)
core  

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

open access: yesFEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan   +4 more
wiley   +1 more source

Annual Report - Marine Biological Laboratory, 1965

open access: yes, 1966
Annual report of the Marine Biological Laboratory in Woods Hole. 1965.
Marine Biological Laboratory (Woods Hole MA)
core  

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

The transport of triterpenoids

open access: yesBiotechnology Notes
Triterpenoids are a group of natural products with promising biological activities. Studying the transport of triterpenoids is of vital importance for designing novel microbial cell factory for efficient bioproduction of triterpenoids, as well as ...
Yubo Fang, Han Xiao
doaj   +1 more source

Annual Report - Marine Biological Laboratory, 1944

open access: yes, 1945
Annual report of the Marine Biological Laboratory in Woods Hole. 1944.
Marine Biological Laboratory (Woods Hole MA)
core  

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Annual Report - Marine Biological Laboratory, 1910

open access: yes, 1911
Annual report of the Marine Biological Laboratory in Woods Hole. 1910.
Marine Biological Laboratory (Woods Hole MA)
core  

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