Results 121 to 130 of about 840,481 (311)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Macroscopic transport by synthetic molecular machines [PDF]

open access: yes, 2005
Nature uses molecular motors and machines in virtually every significant biological process, but demonstrating that simpler artificial structures operating through the same gross mechanisms can be interfaced with—and perform physical tasks in—the ...
Emilio M. Pérez   +24 more
core   +1 more source

Cl−-ATPases: biological active transporters

open access: yesComparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology, 2001
Five widely documented mechanisms of chloride transport across plasma membranes are: anion-coupled antiport; sodium and hydrogen-coupled symport; Cl- channels; and an electrochemical coupling process. No genetic evidence has yet been provided for primary active chloride transport despite numerous reports of cellular Cl(-)-stimulated ATPases co-existing,
Department of Physiology and Department of Medicine, College of Medicine, University of Florida, Gainesville, FL 32610-0274, USA ( host institution )   +2 more
openaire   +3 more sources

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Transport and reaction processes in bioremediation of organic contaminants. 1. Review of bacterial degradation and transport [PDF]

open access: yes, 2003
Bioremediation of contaminants in soil and water involves a complex interplay between transport processes and biological reactions. Equilibrium physical factors such as aqueous solubility, soil adsorption, and phase partitioning indicate the transport ...
Bressler, David C., Gray, Murray R.
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Mathematical modelling of transporter kinetics [PDF]

open access: yes
Membrane transport proteins have recently been discovered to be ubiquitously expressed in the human body and of paramount importance in cellular uptake.
Grandjean, Thomas R. B.
core  

Untersuchungen zur Bedeutung des Kern-Zytoplasma Transports für die biologische Funktion zellulärer Proteine [PDF]

open access: yes, 2005
The thesis entitled „Investigations on the significance of nucleo-cytoplasmic transport for the biological function of cellular proteins" aimed to unreveal molecular mechanisms in order to improve our understanding of the impact of nucleo-cytoplasmic ...
Knauer, Shirley
core  

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Molecular investigation if the rat jejunal active nucleoside transport protein rCNT1 [PDF]

open access: yes, 1998
Active, sodium-dependent nucleoside transport systems have been kinetically described in a number of different mammalian tissues. The recent cloning of several active, mammalian nucleoside transporters belonging to a novel gene family has provided an ...
Hamilton, Stephen Robin
core  

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