Results 131 to 140 of about 840,481 (311)

Learning partial differential equations for biological transport models from noisy spatio-temporal data. [PDF]

Proc Math Phys Eng Sci, 2020
Lagergren JH, Nardini JT, Michael Lavigne G, Rutter EM, Flores KB.   +4 more
europepmc   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Ions in motion: From biological channels to engineered transport systems

Giant
Natural membrane proteins are molecular machines evolved over billions of years, playing crucial roles in various physiological functions by precisely mediating transmembrane transport processes.
Bei Wu, Yifan Yan, Yuting Zhu, Changxing Ji, Yangyang Lin, Chao Lang   +5 more
doaj   +1 more source

Study on Photon Transport Problem Based on the Platform of Molecular Optical Simulation Environment

International Journal of Biomedical Imaging, 2010
As an important molecular imaging modality, optical imaging has attracted increasing attention in the recent years. Since the physical experiment is usually complicated and expensive, research methods based on simulation platforms have obtained extensive
Kuan Peng, Xinbo Gao, Jimin Liang, Xiaochao Qu, Nunu Ren, Xueli Chen, Bin Ma, Jie Tian   +7 more
doaj   +1 more source

Author Correction: The vertical distribution and biological transport of marine microplastics across the epipelagic and mesopelagic water column. [PDF]

Sci Rep, 2020
Choy CA, Robison BH, Gagne TO, Erwin B, Firl E, Halden RU, Hamilton JA, Katija K, Lisin SE, Rolsky C, Van Houtan KS.   +10 more
europepmc   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Repurposing DNA-binding agents as H-bonded organic semiconductors

Nature Communications, 2019
To unlock the potential of biological semiconductors for printed flexible electronics, experimental evidence that reveals the material’s charge transport mechanism is required.
Fengjiao Zhang, Vincent Lemaur, Wookjin Choi, Prapti Kafle, Shu Seki, Jérôme Cornil, David Beljonne, Ying Diao   +7 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Transport of Drugs Through Biological Barriers—An Asset or Risk

Pharmaceutics
Biological barriers are both cellular and enzymatic interfaces between different compartments of a living organism [...]
Anna Weronika Sobańska
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source