Results 221 to 230 of about 5,452,327 (324)

Sample handling in surface sensitive chemical and biological sensing: A practical review of basic fluidics and analyte transport [PDF]

, 2014
Norbert Orgován, Dániel Patkó, Csaba Hős, Sándor Kurunczi, Bálint Szabó, Jeremy J. Ramsden, Róbert Horváth   +6 more
openalex   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Arsenic binds to nuclear transport factors and disrupts nucleocytoplasmic transport. [PDF]

J Cell Sci
Lorentzon E, Lee J, Masaryk J, Keuenhof K, Karlsson N, Galipaud C, Madsen R, Höög JL, Levin DE, Tamás MJ.   +9 more
europepmc   +1 more source

BioFVM: an efficient, parallelized diffusive transport solver for 3-D biological simulations [PDF]

, 2015
Ahmadreza Ghaffarizadeh, Samuel H. Friedman, Paul Macklin   +2 more
openalex   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Passive Membrane Transport Analysis of Drug Mixtures. [PDF]

Anal Chem
Strutt R, Berlanda SF, Dittrich PS.
europepmc   +1 more source

Multi‐omic profiling of squamous cell lung cancer identifies metabolites and related genes associated with squamous cell carcinoma

Molecular Oncology, EarlyView.
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf, Daniel Ehinger, Hans Brunnström, Mats Jönsson, Frida Rosengren, Marija Kotevska, Anna Karlsson, Mattias Aine, Christian Frezza, Maria Planck, Elsa Arbajian   +10 more
wiley   +1 more source

Quantitative imaging of lipid transport in mammalian cells. [PDF]

Nature
Iglesias-Artola JM, Böhlig K, Schuhmann K, Cook KC, Lennartz HM, Schuhmacher M, Barahtjan P, Jiménez López C, Šachl R, Garikapati V, Pombo-Garcia K, Lohmann A, Riegerová P, Hof M, Drobot B, Shevchenko A, Honigmann A, Nadler A.   +17 more
europepmc   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Improving the specimen referral system in Ghana: findings from a landscape assessment. [PDF]

Front Public Health
Nkrumah C, Forson PK, Nkrumah B, Owusu R, Musah MAA, Ahiataku DE, Boateng G, Nanka-Bruce P, Asiedu-Bekoe F, Gudjinu HY, Mills-Pappoe WA, Ayivase JT, Awinibuno IN, Barradas DT.   +13 more
europepmc   +1 more source