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Collagen II enrichment through scAAV6-RNAi-mediated inhibition of matrix-metalloproteinases 3 and 13 in degenerative nucleus-pulposus cells degenerative disc disease and biological treatment strategies. [PDF]
Exp Biol Med (Maywood)Mern DS, Thomé C.
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Biologics for the treatment of noninfectious uveitis
Taiwan Journal of Ophthalmology, 2018 openaire +3 more sources
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
FEBS Open Bio, EarlyView.The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
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Biologic treatments for psoriasis
Journal of the American Academy of Dermatology, 2005P soriasis is a hyperproliferative disorder in which both adaptive and innate immunity play important roles. Traditionally, the treatment of moderate to severe psoriasis has been limited by the safety of many of the drugs that are effective in clearing the disease.
Cindy D, Kipnis +3 more
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Biologics in the treatment of uveitis
Current Opinion in Ophthalmology, 2007This review summarizes the current evidence for biologic therapies in the treatment of uveitis. The review emphasizes published research in this field since 2005.The anti-tumour necrosis factor-alpha infliximab and adalimumab have demonstrated significant efficacy in controlling uveitis associated with seronegative spondyloarthropathies and juvenile ...
Imrie, FR, Dick, AD
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2023
Abstract This chapter reviews the broad range of biological treatments for depersonalization/derealization disorder (DDD), from electroconvulsive therapy and the use of barbiturates/stimulants in the early days of treatment to the various medications that are commonly used today.
Daphne Simeon, Jeffrey Abugel
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Abstract This chapter reviews the broad range of biological treatments for depersonalization/derealization disorder (DDD), from electroconvulsive therapy and the use of barbiturates/stimulants in the early days of treatment to the various medications that are commonly used today.
Daphne Simeon, Jeffrey Abugel
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Biologics in the Treatment of Plantar Fasciitis
Clinics in Podiatric Medicine and Surgery, 2021Plantar fasciitis has been considered an acute inflammatory disorder. However, the local histologic findings represent a more chronic, degenerative state without inflammation. Patients may be stuck in a chronic state of cyclical inflammation leading to tissue degeneration, refractory symptoms, and disability.
Alan, Ng +2 more
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Biologics in the Treatment of Achilles Tendon
Clinics in Podiatric Medicine and Surgery, 2021The treatment of Achilles tendinitis from conservative to minimally invasive to surgery gives patients a wide range of treatment options for this common pathology. The use and role of biologics to augment this treatment is emerging. The use of biologics may enhance the healing potential of the Achilles tendon when conservative treatment fails.
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Incorporating Biologics into the Treatment of Psoriasis
Journal of Cutaneous Medicine & Surgery, 2004Current systemic therapies for psoriasis affect hyperkeratinization 1 or nonspecifically suppress the immune system. 2 While these therapies are effective in the treatment of psoriasis and have been in use for years, they each have specific limitations.
Harvey, Lui +10 more
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