Results 261 to 270 of about 4,500,543 (306)
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Biological treatments for severe asthma
Current Opinion in Allergy & Clinical Immunology, 2019Purpose of review Asthma is a heterogenous disease associated with different phenotypes and endotypes. The unmet needs with severe asthma have led to the emergence of potential therapeutic targets beyond the existing therapies.
Sara M, Assaf, Nicola A, Hanania
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Biological Treatment of Crohn’s Disease
Digestive Diseases, 2012Introduction of biological agents for the treatment of Crohn’s disease (CD) has led to a transformation of the treatment paradigm. Several biological compounds have been approved for patients with CD refractory to conventional treatment: infliximab, adalimumab and certolizumab pegol (and natalizumab in several countries outside the European Union ...
Nielsen, Ole Haagen +4 more
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Biologic Therapies for the Treatment of Asthma
Clinics in Chest Medicine, 2006Asthma is a chronic disease of the airway whose pathogenesis involves the complex interplay between many cell types and inflammatory mediators. The mainstays of therapy, inhaled bronchodilators and corticosteroids, do not target the asthmatic airway specifically and therefore are associated with untoward side effects.
Amy L, Wagelie-Steffen +2 more
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Biologic therapies in the treatment of sarcoidosis
Expert Review of Clinical Immunology, 2016Sarcoidosis is a disease of remarkable heterogeneity in organ manifestation, severity and natural history, characterized by the presence of non-caseating granulomas. The majority of cases are acute and self-limited or remit with short courses of glucocorticoids; however, a proportion progress to a life-threatening obliterative fibrotic type associated ...
Lesley Ann, Saketkoo, Robert P, Baughman
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Biologic Treatment for Hidradenitis Suppurativa
American Journal of Clinical Dermatology, 2019Patients with hidradenitis suppurativa (HS) are often undertreated and there are limited efficacious therapies available for treating this population. Biologics are an emerging therapeutic modality used in the management of many inflammatory conditions including HS.
Kelsey S, Flood +2 more
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2016
According to classification criteria, the spectrum of spondyloarthritis (SpA) covers axial SpA (axSpA), which includes non-radiographic axSpA and ankylosing spondylitis, and peripheral SpA, which overlaps with psoriatic arthritis. Management recommendations for many forms of SpA have been recently published. Treatment of patients with axSpA with active
Juergen Braun +1 more
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According to classification criteria, the spectrum of spondyloarthritis (SpA) covers axial SpA (axSpA), which includes non-radiographic axSpA and ankylosing spondylitis, and peripheral SpA, which overlaps with psoriatic arthritis. Management recommendations for many forms of SpA have been recently published. Treatment of patients with axSpA with active
Juergen Braun +1 more
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Emerging biologics in the treatment of uveitis
Expert Review of Clinical Immunology, 2007The pathogenic mechanisms underlying uveitis syndromes continue to be evaluated using animal models and in the clinical setting. As the complex interactions between ocular immune cells, proinflammatory cytokines, chemokines and cellular adhesion molecules are uncovered, targeted therapies directed against these immune mediators will continue to be ...
Steven, Yeh +2 more
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Biological therapy in the treatment of cancer
British Journal of Nursing, 1995Despite improvements in treatment and survival rates for some types of cancer, there remains a need to develop new treatment strategies for the majority of solid tumours. This article describes the cytokines most commonly used and examines the implications for the patient and nursing management.
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Biologic treatment of human cancer
Current Problems in Cancer, 1995Biologic therapy of cancer is defined as treatment that produces antitumor effects through the action of natural host immune mechanisms or the administration of natural animal substances. Biologic therapy is considered to be a potentially important fourth modality for the treatment of cancer alongside surgery, radiation therapy, and chemotherapy ...
J I, Clark, L M, Weiner
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Biologic treatments in Sjögren's syndrome
La Presse Médicale, 2012Primary Sjögren's Syndrome (pSS) is characterized by focal lymphocytic infiltration of secretory exocrine glands associated with severe dryness of eyes and mouth in particular. Systemic features such as disabling fatigue, cutaneous vasculitis, lung, neurological, haematological or other systemic involvement also occur.
Simon, Bowman, Francesca, Barone
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