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A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
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Biological aging partly mediates the association between physical activity and overactive bladder: evidence from NHANES 2007-2020. [PDF]
Huang J +6 more
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A computational method to estimate the relative biological effectiveness and tumor control probability for low-LET proton irradiations. [PDF]
Chan CC, Hsueh KL, Lai CY, Hsiao YY.
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Pork carcass fabrication economics: drivers of profitability and an explanation of costing models. [PDF]
Bohrer BM.
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The Dynamics of Blood-Count-Derived Inflammatory Indices in the Course of Systemic Treatment for Psoriasis: A Single Center Study. [PDF]
Hołdrowicz A +4 more
europepmc +1 more source
Whole Blood Transcriptome Analysis in Female Adolescents With Depression Accompanied by Nonsuicidal Self-Injury and Suicide Attempt. [PDF]
Zhou Z +9 more
europepmc +1 more source
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The Biological Value of Protein
2015The biological value of a protein extends beyond its amino-acid composition and digestibility, and can be influenced by additional factors in a tissue-specific manner. In healthy individuals, the slow appearance of dietary amino acids in the portal vein and subsequently in the systemic circulation in response to bolus protein ingestion improves ...
Daniel R, Moore, Peter B, Soeters
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