Results 191 to 200 of about 169,450 (313)

Efficacy of Biologics in the Management of Pediatric Asthma: A Single-Center Retrospective Study. [PDF]

Cureus
Huang AP, Silas M, Cherian CG, Livingston FR.   +3 more
europepmc   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Impact of biologicals on revision ESS numbers in CRSwNP in a tertiary care rhinology center. [PDF]

Front Allergy
Adriaenssens JE, Viskens AS, Borgers E, Hellings PW.   +3 more
europepmc   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Case Report: Extending dosing intervals of biologics in adults severe asthma: a case series. [PDF]

Front Allergy
Harada T, Nishigami M, Tanaka H, Inui G, Ishikawa H, Kohno H, Funaki Y, Sakamoto T, Takata M, Okazaki R, Morita M, Kitatani S, Yamasaki A.   +12 more
europepmc   +1 more source

Some MSM Blood Donors Move from a Lifetime Deferral to a One Year Ban “Finally” or “Not Good Enough”? [PDF]

, 2018
Printz, Heather
core   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Pre-clinical development of an enzyme replacement therapy (CPI-601) for CLN1 Batten disease: process development, stability and uptake studies in different species

Neurotherapeutics
Renuka Raman, Ph.D., Ben Horst, Ph.D., Maryam Zare, Ph.D., Zahra Shajrokh, Magdalena Leszczyniecka, Ph.D., Sean Ekins, Ph.D., D.Sc   +5 more
doaj   +1 more source

Biologics-induced cutaneous pseudolymphomas: a narrative review with an illustrative case of brodalumab-induced pseudolymphoma. [PDF]

Drugs Context
Almeida-Silva G, Tribolet de Abreu I, Monteiro F, de Vasconcelos P, Filipe P, Antunes J.   +5 more
europepmc   +1 more source