Results 201 to 210 of about 118,147 (316)

900 TBio BFX 4101: a neoantigen prioritization pipeline for selected tumor-infiltrating lymphocyte therapy

Journal for ImmunoTherapy of Cancer, 2023
Quanyuan He, Christian E Laing, Stewart E Abbot, Tony Collins, Meghan Verschoor, Chantal G Martin, Michael Ciancanelli   +6 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Advance in biologics for chronic rhinosinusitis with nasal polyps. [PDF]

Front Allergy
Di Y, Zeng R, Huang L, Wu Y, Wu Q.
europepmc   +1 more source

Univax Biologics, Inc.: 1993 Annual Report

, 1994
Univax Biologics
core  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Patient Preferences in Hidradenitis Suppurativa Depend on Treatment Experience: Results from APProach-HS. [PDF]

Patient Prefer Adherence
Kromer C, Faverio K, Görig T, Schneider-Burrus S, Benzel F, Goebeler M, Presser D, Schummer P, Schaarschmidt ML, Harth W, Mössner R, Peitsch WK.   +11 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Immunomodulators, Biologics, and 5-ASA for Inflammatory Bowel Disease and Major Adverse Cardiovascular Events in Older Adults.

JAMA Netw Open
Jian Q, Chaudhry NA, Du F, Zimmermann E, Jiao T.   +4 more
europepmc   +1 more source

Vaccinating patients on biologics for atopic disease: Clinical considerations and evidence-based recommendations. [PDF]

Allergy Asthma Proc
Chase NM.
europepmc   +1 more source

Pre-clinical development of an enzyme replacement therapy (CPI-601) for CLN1 Batten disease: process development, stability and uptake studies in different species

Neurotherapeutics
Renuka Raman, Ph.D., Ben Horst, Ph.D., Maryam Zare, Ph.D., Zahra Shajrokh, Magdalena Leszczyniecka, Ph.D., Sean Ekins, Ph.D., D.Sc   +5 more
doaj   +1 more source