Results 31 to 40 of about 3,349,315 (392)
Targeted Delivery of Exosomes Armed with Anti-Cancer Therapeutics
Membranes, 2022 Among extracellular vesicles, exosomes have gained great attention for their role as therapeutic vehicles for delivering various active pharmaceutical ingredients (APIs).
Hojun Choi +7 more
doaj +1 more source
OncoImmunology, 2019 Oncology treatment has been revolutionized by the introduction of immune checkpoint inhibitor drugs, which enable 20–40% of patients to generate anti-tumor immune responses.
Maxine Bauzon +5 more
doaj +1 more source
A Review of the Microbial Production of Bioactive Natural Products and Biologics
Frontiers in Microbiology, 2019 A variety of organisms, such as bacteria, fungi, and plants, produce secondary metabolites, also known as natural products. Natural products have been a prolific source and an inspiration for numerous medical agents with widely divergent chemical ...
Janette V. Pham +11 more
semanticscholar +1 more source
Anti-alarmins in asthma: targeting the airway epithelium with next-generation biologics
European Respiratory Journal, 2020 Monoclonal antibody therapies have significantly improved treatment outcomes for patients with severe asthma; however, a significant disease burden remains. Available biologic treatments, including anti-immunoglobulin (Ig)E, anti-interleukin (IL)-5, anti-
C. Porsbjerg +4 more
semanticscholar +1 more source
The use and impact of monoclonal antibody biologics during pregnancy
Canadian Medical Association Journal, 2021 CMAJ | JULY 26, 2021 | VOLUME 193 | ISSUE 29 E1129 M onoclonal antibody biologics, also known as biologics, have revolutionized the treatment and quality of life of many patients with inflammatory and autoimmune conditions.1 Women of reproductive age are
A. Pham-Huy +4 more
semanticscholar +1 more source
Biologics in Dermatology [PDF]
Pharmaceuticals, 2013 Skin and subcutaneous diseases affect millions of people worldwide, causing significant morbidity. Biologics are becoming increasingly useful for the treatment of many skin diseases, particularly as alternatives for patients who have failed to tolerate or respond to conventional systemic therapies.
Anthony Bewley, David Chandler
openaire +3 more sources
Dermatologic Therapy, 2020 During COVID‐19 outbreak there are discordant opinions toward the impact of biologics in psoriatic (PsO) patients. Thus we performed a single‐center case‐control study in Lombardia, the Italian region with the higher number of COVID‐19 confirmed cases ...
G. Damiani +3 more
semanticscholar +1 more source
Management of Chronic Rhinosinusitis with Nasal Polyposis in the Era of Biologics
Journal of Asthma and Allergy, 2021 Purpose of Review Chronic rhinosinusitis with nasal polyposis (CRSwNP) is a phenotypic designation of the broader condition of chronic rhinosinusitis. The advent of targeted biologics has shown promise in targeting different aspects of the inflammatory ...
Justin C Morse, Craig Miller, B. Senior
semanticscholar +1 more source
Viewpoint on handling anti-TNF failure in psoriasis [PDF]
, 2013 An association among the occurrence of antidrug antibodies (ADAs), diminished trough serum drug levels (TSDLs) and non-response or loss of response has been described for several tumor necrosis factor alpha (TNF) blocking agents in a variety of diseases,
BRACKE, STEFANIE, Lambert, Jo
core +1 more source
Dose Tapering of Biologics in Patients with Psoriasis: A Scoping Review
Drugs, 2021 Biologics serve as a cornerstone in psoriasis treatment, with low disease activity or sometimes even clinical remission as a realistic treatment outcome. So far, it is unclear whether biologics should be tapered when this target is achieved.
C. Michielsens +4 more
semanticscholar +1 more source