Results 31 to 40 of about 13,847 (134)

Comparaison de deux techniques d'identification des souches de levures de vinification basées sur le polymorphisme de l'ADN génomique: réaction de polymérisation en chaine (PCR) et analyse des caryotypes (électrophorèse en champ pulsé)

OENO One, 1994
Une nouvelle technique de la biologie moléculaire, la réaction de polymérisation en chaine (PCR) permet l'identification des souches de levures de vinification.
Isabelle Masneuf-Pomarède, Denis Dubourdieu   +1 more
doaj   +1 more source

Cytosolic sequestration of the vitamin D receptor as a therapeutic option for vitamin D-induced hypercalcemia

Nature Communications, 2020
Current therapeutic strategies for vitamin D-induced hypercalcemia are poorly efficient. Here the authors identify a new interaction between the vitamin D receptor (VDR) and WBP4 controlling the subcellular localization of VDR and show that ZK168281, a ...
Daniela Rovito, Anna Y. Belorusova, Sandra Chalhoub, Anna-Isavella Rerra, Elvire Guiot, Arnaud Molin, Agnès Linglart, Natacha Rochel, Gilles Laverny, Daniel Metzger   +9 more
doaj   +1 more source

Quantitative analysis of DNA‐GATA1 binding alterations linked to hematopoietic disorders

The FEBS Journal, EarlyView.
Native holdup allows the quantitative determination of affinities between full‐length transcription factors and DNA. Mutations in either the protein or the DNA can modulate binding strength, which can be precisely quantified using this approach. Applied to GATA1, it revealed mutations that alter DNA binding.
Boglarka Zambo, Bastien Morlet, Luc Negroni, Orsolya Mózner, Balázs Sarkadi, Gilles Travé, Gergo Gogl   +6 more
wiley   +1 more source

Involvement of the Bacillus SecYEG Pathway in Biosurfactant Production and Biofilm Formation

International Journal of Microbiology
With Bacillus species, about 30% of extracellular proteins are translocated through the cytoplasmic membrane, coordinated by the Sec translocase. This system mainly consists of the cytoplasmic ATPase SecA and the membrane-embedded SecYEG channel.
Frédéric Yannick Okouakoua, Christian Aimé Kayath, Saturnin Nicaise Mokemiabeka, David Charles Roland Moukala, Moïse Doria Kaya-Ongoto, Etienne Nguimbi   +5 more
doaj   +1 more source

BTG2 bridges PABPC1 RNA-binding domains and CAF1 deadenylase to control cell proliferation

Nature Communications, 2016
BTG2 promotes mRNA poly(A) tail shortening and regulates cellular differentiation. Here, Stupfler et al. show that the BTG2 APRO domain interacts with PABPC1 RRM1, allowing the former to recruit and stimulate the poly(A) tail shortening activity of CAF1 ...
Benjamin Stupfler, Catherine Birck, Bertrand Séraphin, Fabienne Mauxion   +3 more
doaj   +1 more source

Lipid-depleted diet perturbs membrane composition and intracellular transport in lactating mammary cells

Journal of Lipid Research, 1997
When rats were fed a control or a lipid-depleted diet for five generations, reproduction was not disturbed but pup growth was affected. The membrane organization and the secretory activity of mammary epithelial cells from these lactating rats were ...
M Ollivier-Bousquet, F Lavialle, P Guesnet, D Rainteau, G Durand   +4 more
doaj   +1 more source

TopoDoE: a design of experiment strategy for selection and refinement in ensembles of executable gene regulatory networks

BMC Bioinformatics
Background Inference of Gene Regulatory Networks (GRNs) is a difficult and long-standing question in Systems Biology. Numerous approaches have been proposed with the latest methods exploring the richness of single-cell data.
Matteo Bouvier, Souad Zreika, Elodie Vallin, Camille Fourneaux, Sandrine Gonin-Giraud, Arnaud Bonnaffoux, Olivier Gandrillon   +6 more
doaj   +1 more source

Techniques de biologie moléculaire comme outils de gestion des pêches : bilan et perspectives

Knowledge and Management of Aquatic Ecosystems, 1994
Le concept de stock stipule que la diversité génétique et la structure populationnelle des espèces doivent être reconnues et préservées afin d'assurer une utilisation optimale de la ressource.
BERNATCHEZ L.
doaj   +1 more source

Comparison of the life cycles of two populations of the polychaete Pereinereis cf. cultrifera from the Bay of Algiers (Mediterranean Sea)

Scientia Marina, 2008
The benthic phases of the life cycles of two populations of the polychaete Pereinereis cultrifera from the Bay of Algiers were investigated using field surveys. We found no differences in the life cycle of the two populations.
Leila Rouabah, Abdelkader Rouabah, Sana Ferroudj, Patrick Scaps   +3 more
doaj   +1 more source