Results 41 to 50 of about 14,662 (185)
Senescence controls prostatic neoplasia driven by Pten loss
We report that Pten (phosphatase and tensin homologue) ablation in prostatic epithelial cells of adult mice promotes cell proliferation to generate prostatic intraepithelial neoplasia.
Maxime Parisotto +3 more
doaj +1 more source
The benthic phases of the life cycles of two populations of the polychaete Pereinereis cultrifera from the Bay of Algiers were investigated using field surveys. We found no differences in the life cycle of the two populations.
Leila Rouabah +3 more
doaj +1 more source
Caenorhabditis elegans as an in vivo model system for human inherited primary arrhythmia syndromes
Abstract figure legend Most genes involved in inherited primary arrhythmia syndromes (IPAS) are conserved in Caenorhabditis elegans, where genetic manipulation enables functional characterization of variants, identification of regulatory proteins, and in vivo drug testing.
Antoine Delinière +6 more
wiley +1 more source
Une étude a été menée au secteur Izeli du ranch de Mushie (Province de Maï-Ndombe) en République Démocratique du Congo du 3 Août au 5 Septembre 2014 et du 6 Février au 7 Mars 2015.
Edouard Telamanu BAFWANGA +3 more
doaj
Techniques de biologie moléculaire comme outils de gestion des pêches : bilan et perspectives
Le concept de stock stipule que la diversité génétique et la structure populationnelle des espèces doivent être reconnues et préservées afin d'assurer une utilisation optimale de la ressource.
BERNATCHEZ L.
doaj +1 more source
Regulation of gene expression involves a complex and dynamic dialogue between transcription factors, chromatin remodelling and modification complexes and the basal transcription machinery.
Thomas Kleiber +4 more
doaj +1 more source
RXR Gamma Enables Oligodendrocyte Differentiation by Suppressing Sonic Hedgehog Signaling
Using pharmacogenetic approaches, Baldassarro et al. demonstrate that RXRγ suppresses the SHH signaling pathway in OPCs to ensure their efficient differentiation following T3 stimulation. Accordingly, Rxrg−/− OPCs displayed compromised differentiation which was normalized by the pharmacological inhibition of the hyperactive SHH pathway.
Vito Antonio Baldassarro +4 more
wiley +1 more source
Background Mitochondria require thousands of proteins to fulfill their essential function in energy production and other fundamental biological processes.
Mickaële Hémono +4 more
doaj +1 more source
ABSTRACT Background and Objectives Hepatitis B virus (HBV) infection remains a major global health burden, with disease progression influenced by host genetic and immune factors, including variants in the mannose‐binding lectin 2 (MBL2) gene. This study aimed to evaluate the association between MBL2 polymorphisms and clinical outcomes of HBV infection ...
Minane Nafissa Triande +13 more
wiley +1 more source
NimA promotes cell adhesion at the blood brain barrier of the Drosophila nervous system
Glial cells are crucial for nervous system development and function by clearing debris, protecting neurons and ensuring neuronal survival. In Drosophila, glia form the blood–brain barrier, which regulates neural stem cell proliferation and shields the ...
Rosy Sakr +7 more
doaj +1 more source

