Results 41 to 50 of about 38,835 (164)
klf2a couples mechanotransduction and zebrafish valve morphogenesis through fibronectin synthesis
Nature Communications, 2016 In the developing heart, blood flow transmits mechanical signals to progenitor cells that ultimately leads to valve formation. Here, the authors identify the origin of the valve progenitor cells and fibronectin1bas a transcriptional target of the ...
Emily Steed +5 more
doaj +1 more source
Journal of Lipid Research, 1997 When rats were fed a control or a lipid-depleted diet for five generations, reproduction was not disturbed but pup growth was affected. The membrane organization and the secretory activity of mammary epithelial cells from these lactating rats were ...
M Ollivier-Bousquet +4 more
doaj +1 more source
British Journal of Pharmacology, EarlyView.IS39, a novel non‐peptide PKR1 agonist, confers cardioprotection against doxorubicin‐induced toxicity. IS39 activates PKR1‐mediated pro‐survival signalling in cardiomyocytes, reducing reactive oxygen species (ROS), DNA damage and fibrosis markers. In vivo, IS39 preserves cardiac geometry and function in mice exposed to chronic doxorubicin challenge ...
Anais Audebrand +8 more
wiley +1 more source
Interaction of lncRNA LENT with DHX36 regulates translation and suppresses autophagy in melanoma
Cell Death and DiseaseThe melanocyte lineage-determining Microphthalmia-associated transcription factor (MITF) drives proliferation and survival of melanocytic melanoma cells through regulation of both coding genes and long non-coding RNAs (LncRNAs).
Alexandre Haller +11 more
doaj +1 more source
BTG2 bridges PABPC1 RNA-binding domains and CAF1 deadenylase to control cell proliferation
Nature Communications, 2016 BTG2 promotes mRNA poly(A) tail shortening and regulates cellular differentiation. Here, Stupfler et al. show that the BTG2 APRO domain interacts with PABPC1 RRM1, allowing the former to recruit and stimulate the poly(A) tail shortening activity of CAF1 ...
Benjamin Stupfler +3 more
doaj +1 more source
OENO One, 1994 Une nouvelle technique de la biologie moléculaire, la réaction de polymérisation en chaine (PCR) permet l'identification des souches de levures de vinification.
Isabelle Masneuf-Pomarède +1 more
doaj +1 more source
Troisième conférence internationale sur les ravageurs en agriculture [PDF]
, 1993 La contribution des techniques de la biologie moléculaire en Acarologie est présentée sur la base de résultats obtenus chez les acariens phytophages et prédateurs de phytophages.
Gutierrez, Jean +2 more
core
Quantitative analysis of DNA‐GATA1 binding alterations linked to hematopoietic disorders
The FEBS Journal, EarlyView.Native holdup allows the quantitative determination of affinities between full‐length transcription factors and DNA. Mutations in either the protein or the DNA can modulate binding strength, which can be precisely quantified using this approach. Applied to GATA1, it revealed mutations that alter DNA binding.
Boglarka Zambo +6 more
wiley +1 more source
Involvement of the Bacillus SecYEG Pathway in Biosurfactant Production and Biofilm Formation
International Journal of MicrobiologyWith Bacillus species, about 30% of extracellular proteins are translocated through the cytoplasmic membrane, coordinated by the Sec translocase. This system mainly consists of the cytoplasmic ATPase SecA and the membrane-embedded SecYEG channel.
Frédéric Yannick Okouakoua +5 more
doaj +1 more source
Senescence controls prostatic neoplasia driven by Pten loss
Molecular & Cellular Oncology, 2019 We report that Pten (phosphatase and tensin homologue) ablation in prostatic epithelial cells of adult mice promotes cell proliferation to generate prostatic intraepithelial neoplasia.
Maxime Parisotto +3 more
doaj +1 more source