Results 91 to 100 of about 907,769 (296)

Philosophy of Synthetic Biology

Iranian South Medical Journal, 2018
Synthetic biology is a novel branch of biological sciences. The creation of a synthetic microorganisms with minimal genome compatible with life by Craig Venter had provoked the prior hot philosophical discussions about the nature of life.
Iraj Nabipour
doaj  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Flow matching meets biology and life science: a survey

npj Artificial Intelligence
Nature Portfolio Journal Artificial Intelligence, 34 ...
Zihao Li 0006, Zhichen Zeng 0001, Xiao Lin 0016, Feihao Fang, Yanru Qu, Zhe Xu 0007, Zhining Liu 0002, Xuying Ning, Tianxin Wei, Ge Liu, Hanghang Tong, Jingrui He   +11 more
openaire   +2 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Mathematical modeling of evolution., Volume 1, One-locus and multi-locus theory and recombination / De Gruyter series in mathematics and life sciences ;, 8/1./ Igor M. Rouzine.

, 2021
The De Gruyter Series in Mathematics and Life Sciences is devoted to the publication of monographs in the field. They cover topics and methods in fields of current interest that use mathematical approaches to understand and explain, model and influence ...
Rouzine Igor M.,
core  

Life sciences [PDF]

, 1991
This document is the 1989--1990 Annual Report for the Life Sciences Divisions of the University of California/Lawrence Berkeley Laboratory. Specific progress reports are included for the Cell and Molecular Biology Division, the Research Medicine and ...
Day, L.
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

AI reshaping life sciences: intelligent transformation, application challenges, and future convergence in neuroscience, biology, and medicine

Frontiers in Digital Health
The rapid advancement of artificial intelligence (AI) is profoundly transforming research paradigms and clinical practices across neuroscience, biology, and medicine with unprecedented depth and breadth. Leveraging its robust data-processing capabilities,
Jiahuan Gong, Zihao Zhao, Xinxin Niu, Yanan Ji, Hualin Sun, Yuntian Shen, Bingqian Chen, Bei Wu   +7 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Evaluation of a Questionnaire Measuring University Students' Sense of Belonging to and Involvement in a Biology Department

, 2020
Sense of belonging and involvement has shown to be positively associated with academic achievement and retention. We argue that a focus on sense of belonging and involvement specifically at the departmental level is valuable, yet rarely discussed in the ...
Knekta, Eva, Chatzikyriakidou, Kyriaki, McCartney, Melissa   +2 more
core   +1 more source