Results 81 to 90 of about 907,769 (296)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Kahjurite jätkusuutlikud tõrjestrateegiad rapsi integreeritud taimekaitses
A Thesis for applying for the degree of Doctor of Philosophy in Agricultural Sciences.Väitekiri filosoofiadoktorikraaditaotlemiseks põllumajanduse erialal.ABSTRACT.
Vilumets, Silva
core +1 more source
Molecules, 2011 Objects, goals, and main methods as well as perspectives of chemical biology are discussed. This review is focused on the fundamental aspects of this emerging field of life sciences: chemical space, the small molecule library and chemical sensibilization
Vladimir V. Kouznetsov +2 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
PLOS Biology at 20: Exploring possible futures.
, 2023 Twenty years ago this month, PLOS Biology was launched, helping to catalyze a movement that has transformed publishing in the life sciences.
PLOS Biology staff editors +1 more
core +1 more source
The Business Machine in Biology—The Commercialization of AI in the Life Sciences
IEEE Annals of the History of Computing, 2022 This paper traces one important trajectory in the history of expert systems. Through a collaboration between Edward Feigenbaum and the geneticist Joshua Lederberg, Nobel Laureate in Medicine, AI became deeply connected to the life sciences. Biology was a crucial test-bed for some of Feigenbaums systems and, in the long term, these systems had a ...
openaire +2 more sources
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Whence philosophy of biology? [PDF]
, 2006 A consensus exists among contemporary philosophers of biology about the history of their field. According to the received view, mainstream philosophy of science in the 1930s, 40s, and 50s focused on physics and general epistemology, neglecting analyses ...
Byron (formerly Baker), Jason M.
core
Presentist Social Functionalism: Bringing Contemporary Evolutionary Biology to the Social Sciences [PDF]
This open access book presents and defends a new approach towards social functionalism: Presentist Social Functionalism. This approach draws on recent developments in evolutionary biology and philosophy of biology to provide a more compelling theoretical
Schulz, Armin W.
core +1 more source