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Considering Grand Challenges in Biology Education : Rationales and Proposals for Future Investigations to Guide Instruction and Enhance Student Understanding in the Life Sciences [PDF]
, 2018 An international group of biology education researchers offer their views on areas of scholarship that might positively impact our understanding of teaching and learning in biology and potentially inform practices in biology and life science instruction.
McComas, William +23 more
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FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
, 2018 This fly food preparation recipe is credited to "Media Prep Lab, Temasek Life Sciences Laboratories, July 2009." It was used at both the Temasek Life Sciences Laboratories and the Institute of Molecular and Cell Biology in Singapore from before 2011 and
Temasek Life Sciences Laboratories (8221263) +1 more
core +1 more source
Systems Biology: Taking a Big Picture
Journal of the Dow University of Health Sciences, 2013 There are more things in heaven and earth, Horatio, than are dreamt of in your philosophy†(Shakespeare, Hamlet). This philosophical profundity of William Shakespeare may correctly represent the current status of our understanding of universe.
Mushtaq Hussain, Muhammad Rafiq Khanani
doaj +4 more sources
La biophilosophie de Georges Canguilhem [PDF]
S&F_scienzaefilosofia.it, 2017 Georges Canguilhem's Biophilosophy The eminent French biologist and historian of biology, François Jacob, once notoriously declared «On n’interroge plus la vie dans les laboratoires»: laboratory research no longer inquires into the notion of “Life ...
WOLFE, CHARLES T.
doaj
Revista Brasileira de Ensino de Ciência e Tecnologia, 2018 A teleological explanation is linked to the idea of finality, often adopting terms such as purpose, goal and function, and have played a central role throughout the history of life sciences.
Valdir Lamim-Guedes
doaj +1 more source
Eleven quick tips for running an interdisciplinary short course for new graduate students. [PDF]
PLoS Computational Biology, 2018 Quantitative reasoning and techniques are increasingly ubiquitous across the life sciences. However, new graduate researchers with a biology background are often not equipped with the skills that are required to utilize such techniques correctly and ...
Timothy E Saunders +4 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source