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Explanation in Biology: Reduction, Pluralism, and Explanatory Aims [PDF]
This essay analyzes and develops recent views about explanation in biology. Philosophers of biology have parted with the received deductive-nomological model of scientific explanation primarily by attempting to capture actual biological theorizing and ...
Brigandt, Ingo, Ingo Brigandt
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Correction Following publication of the original article [1], it came to the attention of the authors that they had omitted to acknowledge the University of Parma.
Anna Rita Paolacci +8 more
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Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
MODERN BIOLOGY & VISIONS OF HUMANITY
Preface -- Introduction -- Forum life sciences and the belief in progress -- Science and progress / Axel Kahn -- Beyond enlightenment: the rise of a culture of life / Karin Knorr Cetina -- Life sciences, the image of man and progress / Evandro ...
European Group on Life Sciences
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Eostaimede lehtede struktuur, füsioloogia ja hormoonvastused
A Thesis for applying for the degree of Doctor of Philosophy in Environmental Sciences and Applied Biology.Väitekiri filosoofiadoktori kraadi taotlemiseks rakendusbioloogia erialal.ABSTRACT.
Wuyun, Tana
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The Philosophy of Molecular and Developmental Biology [PDF]
Philosophical discussion of molecular and developmental biology began in the late 1960s with the use of genetics as a test case for models of theory reduction.
Griffiths, Paul Edmund
core
The biosocial event : responding to innovation in the life sciences [PDF]
Innovation in the life sciences calls for reflection on how sociologies separate and relate life processes and social processes. To this end we introduce the concept of the ‘biosocial event’.
Motzkau, J., Lee, Nick, Motzkau, Johanna
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90 éves a Magyar Tudományos Akadémia Ökológiai Kutatóközpont Balatoni Limnológiai Intézete
The Lake Balaton Institute of Limnology of the Ecological Research Centre of the Hungarian Academy of Arts and Sciences is 90 years old. The Balaton Limnology Institute of the Hungarian Academy of Arts and Sciences celebrated the 90th anniversary of its ...
László Fésüs
doaj

