Results 101 to 110 of about 181,612 (311)
Computing one-dimensional global manifolds of Poincaré maps by continuation [PDF]
, 2005 We present an algorithm to compute one-dimensional stable and unstable manifolds of saddle periodic orbits in a Poincaré section. The computation is set up as a boundary value problem by restricting the beginning and end points of orbit segments to the ...
England, James +6 more
core +1 more source
Brief history of natural sciences for nature-inspired computing in engineering
Journal of Civil Engineering and Management, 2016 The goal of the authors is adroit integration of three mainstream disciplines of the natural sciences, physics, chemistry and biology to create novel problem solving paradigms.
Nazmul Siddique, Hojjat Adeli
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Biological Computing: At the Crossroads of Engineering and Science [PDF]
, 2023 Imagine you are a salesman needing to visit 100 cities connected by a set of roads. Can you do it while stopping in each city only once? Even a supercomputer working at 1 trillion operations per second would take longer than the age of the universe to ...
Khodor, Julia
core
Molecular Computing and Bioinformatics
Molecules, 2019 Molecular computing and bioinformatics are two important interdisciplinary sciences that study molecules and computers. Molecular computing is a branch of computing that uses DNA, biochemistry, and molecular biology hardware, instead of traditional ...
Xin Liang, Wen Zhu, Zhibin Lv, Quan Zou
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
State of the Art in Parallel Computing with R [PDF]
R is a mature open-source programming language for statistical computing and graphics. Many areas of statistical research are experiencing rapid growth in the size of data sets. Methodological advances drive increased use of simulations.
Hao Yu +5 more
core +1 more source
Systems Biology and Advanced Computing [PDF]
, 2007 In this paper we show some applications of Advanced and Parallel Computing to the study of mathematical models in Systems Biology and in particular of the networks of biochemical reactions occurring inside a cell.
P. LANUCARA +3 more
core
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source