Results 91 to 100 of about 3,510,493 (329)

Integrating genetics and epigenetics in breast cancer: biological insights, experimental, computational methods and therapeutic potential

BMC Systems Biology, 2015
BackgroundDevelopment of human cancer can proceed through the accumulation of different genetic changes affecting the structure and function of the genome.
C. Cava, G. Bertoli, I. Castiglioni
semanticscholar   +1 more source

Goodbye flat lymphoma biology

FEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria, Cèlia Dobaño‐López, Patricia Pérez‐Galán, Christine Bezombes   +3 more
wiley   +1 more source

THE ROLE OF WILD BIRDS IN PRESERVATION AND PREVALENCE OF AVIAN PARAMYXOVIRUS SEROTYPE 1 (NEWCASTLE DISEASE VIRUSES) IN SIBERIA AND THE FAR EAST, RUSSIA

Юг России: экология, развитие, 2016
The aim is to evaluate ecological diversity of wild birds in Siberia and the Russian Far East, which are carriers of Newcastle disease virus that belongs to potentially dangerous pathogen for poultry.Methods.
A. V. Glushchenko, K. S. Yurchenko, A. K. Yurlov, Yu. G. Yushkov, M. Yu. Shchelkanov, A. M. Shestopalov   +5 more
doaj   +1 more source

Additional file 2 of Dysregulation of ribosome-related genes in ankylosing spondylitis: a systems biology approach and experimental method

, 2021
Additional file 2: Supplementary File 2.pdf.
Lari, Arezou, Pourbadie, Hamid Gholami, Sharifi-Zarchi, Ali, Akhtari, Maryam, Samimi, Leila Nejatbakhsh, Jamshidi, Ahmadreza, Mahmoudi, Mahdi   +6 more
openaire   +1 more source

Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position

FEBS Letters, EarlyView.
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield, Torsten Kleffmann, David J. Saul, Sigurd M. Wilbanks   +3 more
wiley   +1 more source

DRAWING BASED MODELLING BERBANTUAN EBEAM CAPTURE UNTUK MENSTIMULASI REPRESENTASI MIKROSKOPIS CALON GURU BIOLOGI

Jurnal BIOEDUIN, 2019
This study aims to determine the drawing based modeling implementation aid eBeam Capture in stimulating the Microscopic Representation of Prospective Biology Teachers in the Digital Era.
Tomi Hidayat, Adi Rahmat, Sri Redjeki, Taufik Rahman   +3 more
doaj   +1 more source

Microfluidics for understanding model organisms

Nature Communications, 2022
Building small-scale tools for biology research eliminates the need for time-consuming methods and enables novel experimental paradigms. Here, the authors discuss microfluidics' potential for manipulating or stimulating model organisms and identify ...
Nolan Frey, Utku M. Sönmez, Jonathan Minden, Philip LeDuc   +3 more
doaj   +1 more source

Additional file 1 of Dysregulation of ribosome-related genes in ankylosing spondylitis: a systems biology approach and experimental method

, 2021
Additional file 1: Supplementary File 1.pdf. Characteristics of subjects involved in the microarray dataset.
Lari, Arezou, Pourbadie, Hamid Gholami, Sharifi-Zarchi, Ali, Akhtari, Maryam, Samimi, Leila Nejatbakhsh, Jamshidi, Ahmadreza, Mahmoudi, Mahdi   +6 more
openaire   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

FEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan, Victoria Scarpelli, Marten Exterkate   +2 more
wiley   +1 more source

C‐mannosylation promotes ADAMTS1 activation and secretion in human testicular germ cell tumor NEC8 cells

FEBS Letters, EarlyView.
C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi, Takehiro Suzuki, Ryota Kawahara, Natsumi Harai, Naoshi Dohmae, Siro Simizu   +5 more
wiley   +1 more source