Results 101 to 110 of about 2,453,647 (296)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Physics of Transport and Traffic Phenomena in Biology: from molecular motors and cells to organisms

, 2005
Traffic-like collective movements are observed at almost all levels of biological systems. Molecular motor proteins like, for example, kinesin and dynein, which are the vehicles of almost all intra-cellular transport in eukayotic cells, sometimes ...
Aghababaie, Anderson, Anderson, Anderson, Anderson, Anderson, Andreas Schadschneider, Antal, Aridor, Aridor, Arndt, Arndt, Astumian, Bonabeau, Bonabeau, Bonabeau, Bonabeau, Bonabeau, Burd, Burd, Burstedde, Camazine, Chopard, Chopard, Chou, Chowdhury, Chowdhury, Chowdhury, Coffey, Couzin, de Gier, Debashish Chowdhury, Derenyi, Derenyi, Derrida, Derrida, Derrida, Dorigo, Ebneth, Edelstein-Keshet, Evans, Evans, Evans, Evans, Evans, Feynman, Fisher, Frey, Fukui, Gautrais, Gipps, Goldstein, Goldstein, Goldstein, Goldstein, Goldstein, Grimm, Gross, Gueron, Hackney, Harms, Helbing, Helbing, Helbing, Helbing, Helbing, Helbing, Henderson, Hiratsuka, Hirokawa, Howard, Huang, Hughes, Hughes, Hölldobler, Jackson, Janowsky, John, Juhasz, Juhasz, Jülicher, Kafri, Katsuhiro Nishinari, Kirchner, Kirchner, Kirchner, Klein, Klumpp, Klumpp, Klumpp, Klumpp, Klüpfel, Kolomeisky, Krieger, Krug, Krug, Kruse, Ktitarev, Lakatos, Leduc, Lee, Lipowsky, Lipowsky, MacDonald, MacDonald, Mahnke, Mai, Mandelkow, Marchesoni, Marconi, Marro, Mikhailov, Mogilner, Mukherji, Muramatsu, Nagase, Nakayama, Nedlec, Nedlec, Nieuwenhuizen, Nieuwenhuizen, Nishinari, Nishinari, Nitta, O'Loan, O'Loan, Odell, Okada, Okada, Okada, Parmeggiani, Parmeggiani, Popescu, Popkov, Popkov, Popkov, Railsback, Rajewsky, Rajewsky, Ratnieks, Ratnieks, Rauch, Reimann, Risken, Saffarian, Sankararaman, Schadschneider, Schmittmann, Schweitzer, Schütz, Schütz, Shaw, Shaw, Shaw, Smoluchowski, Stamer, Surrey, Theraulaz, Theraulaz, Thompson, Tripathi, Watmough, Weibel, Welte, Whittaker, Wilson, Wolfram, Wolfram, Ziebert   +168 more
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Effects of TPACK-based instruction on secondary school students’ biology achievement and perception in education district VI, Lagos State

International Journal of Studies in Psychology
Biology education increasingly demands innovative approaches that integrate technology, pedagogy, and content to address students’ diverse learning needs.
Iskeel Sina Raheem
doaj   +1 more source

Analytical light scattering methods in molecular and structural biology: Experimental aspects and results

, 2018
with supllmentary material, 7 figures, 11 supplementary figures and 42 ...
openaire   +2 more sources

Does replication groups scoring reduce false positive rate in SNP interaction discovery? [PDF]

, 2010
BACKGROUNG. Computational methods that infer single nucleotide polymorphism (SNP) interactions from phenotype data may uncover new biological mechanisms in non-Mendelian diseases. However, practical aspects of such analysis face many problems.
Curk, Tomaz, Demsar, Janez, Toplak, Marko, Zupan, Blaz   +3 more
core  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

THE EFFECTIVENESS OF THE APPLICATION OF THE METHODOLOGY OF PROJECT-BASED LEARNING IN GENERAL BIOLOGY IN THE FORMATION OF STUDENTS' SUBJECT AND META-SUBJECT COMPETENCIES

Russian Journal of Education and Psychology
Background. The system-activity approach as the methodological basis of modern educational standards has determined the need to involve schoolchildren in project activities at all levels of general education in accordance with the principle of continuity
Andzhelika M. Shekhmirzova, Lyudmila V. Gribina, Fatima A. Tuguz, Nafiset S. Blagoz   +3 more
doaj   +1 more source

Chemical Biology Gateways to Mapping Location, Association, and Pathway Responsivity

Frontiers in Chemistry, 2019
Here we discuss, how by applying chemical concepts to biological problems, methods have been developed to map spatiotemporal regulation of proteins and small-molecule modulation of proteome signaling responses.
Marcus J. C. Long, Xuyu Liu, Yimon Aye
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source