Results 121 to 130 of about 20,738,755 (301)

Advances in Cancer Biology and Experimental Anticancer Therapies (2nd Edition)

Following the invitation from Biomedicines, we launched a second edition of the Special Issue “Advances in Cancer Biology and Experimental Anticancer Therapies”, as we believe it is truly important to continue focusing on advances in cancer biology and ...
Letizia Polito, Polito, Letizia, Gajda, Ewa, Ewa Gajda, Polito, L, Gajda, E   +5 more
core   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Improving Creativity of the Future Physics Teachers Through General Biology Learning Based on CTL with Experimental Method

Indonesian Journal of Science and Education, 2018
<p>The purpose of this research was to increase creativity of the future physicsteachersthrough General Biology learning based on CTL with experimental method. The type of research used in this study was classroom action research (CAR) through 4cycles of activity.
openaire   +3 more sources

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Protein Expression Analysis by Western Blot and Protein–Protein Interactions

, 2019
Capítulo del libro "Iovino F. (eds) Streptococcus pneumoniae. Methods in Molecular Biology, vol 1968. Humana Press, New York, NY"Western blot analysis is widely used for detecting protein expression, analysis of protein–protein interactions, and ...
Cima-Cabal, María Dolores, de los Toyos, Juan R, Cima Cabal, María Dolores, Vázquez, Fernando, María del Mar García-Suárez, Vázquez Valdés, Fernando, Toyos González, Juan Ramón de los, Juan R. de los Toyos, García-Suárez, María del Mar, María Dolores Cima-Cabal, García Suárez, María del Mar, Fernando Vazquez, García-Suárez, María del Mar (1), Cima-Cabal, María Dolores (1)   +13 more
core   +1 more source

Effectiveness of Digital Gamification in Biology Concept Comprehension and Learner Motivation in Secondary Schools

Journal of Learning for Development
Digital technology has increasingly transformed the landscape of science education, positioning gamification as a powerful pedagogical tool to enhance learner engagement and comprehension.
Sheilla Indiaka, Waweru Mwangi, Jael Sanyanda   +2 more
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Medaka: Biology, Management, and Experimental Protocols

Medaka: Biology, Management, and Experimental Protocols, written by experienced researchers and reviewed by international leaders in the medaka field will provide details on how to set up and maintain medaka colonies in animal facilities, how to ...
丸山 耕一, 581245, 581244, 581246, Maruyama, Kouichi, et.al   +5 more
core  

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source