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A Study on Simulation Methods in Academic Success With Reference To Teaching Biology for Education Students [PDF]
, 2016 The main objective of this study is to determine the utility of simulation methods in biology teaching for nursing students and academic success. 100 students (50 control, 50 experimental) who studied at Srinivasa Teacher Training School, Kalikiri ...
Sasikala, P., Tanyong, Siriwan
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Discover EducationThis study investigated the effectiveness of the Guided Inquiry-Based Laboratory Experiments Enriched Instructional (GIBLEI) approach in improving tenth-grade students’ understanding of biology concepts. A concurrent embedded mixed-method research design
Ashebir Mekonnen Chengere +3 more
doaj +1 more source
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
FEBS Letters, EarlyView.The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
Computational Probability for Systems Biology
Stochastic models of biological networks properly take the randomness of molecular dynamics in living cells into account. Numerical solution approaches inspired by computational methods from applied probability can efficiently yield accurate results and ...
Werner Sandmann, Verena Wolf. +2 more
core +1 more source
Implications of Big Data for cell biology
, 2015 “Big Data” has surpassed “systems biology” and “omics” as the hottest buzzword in the biological sciences, but is there any substance behind the hype? Certainly, we have learned about various aspects of cell and molecular biology from the many individual
Dolinski, Kara, Troyanskaya, Olga
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Фактори експериментальної еволюції організмів, 2015 Aims. Studying of xenogeneic MSC efficacy in treatment of atrophic rhinitis in mice and detection of human DNA in recipient different organs. Methods. Molecular biology and cell biology methods, animal model obtaining. Results.
О. Г. Дерябіна +5 more
doaj
How thoughtful experimental design can empower biologists in the omics era
Nature CommunicationsThe modern biology toolbox continues to evolve, as cutting-edge molecular techniques complement some classic approaches and replace others. However, statistical literacy and experimental design remain critical to the success of any empirical research ...
Maggie R. Wagner, Manuel Kleiner
doaj +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source