Results 1 to 10 of about 11,138,623 (376)

A General Introduction to Glucocorticoid Biology [PDF]

open access: yesFrontiers in Immunology, 2019
Glucocorticoids (GCs) are steroid hormones widely used for the treatment of inflammation, autoimmune diseases, and cancer. To exert their broad physiological and therapeutic effects, GCs bind to the GC receptor (GR) which belongs to the nuclear receptor ...
Steven Timmermans   +5 more
doaj   +9 more sources

Biology, General and Medical [PDF]

open access: bronzeSOUTHERN MEDICAL JOURNAL, 1911
Includes index. ; Includes bibliographical references. ; Mode of access: Internet.
A. D.
semanticscholar   +4 more sources

A general protocol for the generation of Nanobodies for structural biology [PDF]

open access: greenNature Protocols, 2014
There is growing interest in using antibodies as auxiliary tools to crystallize proteins. Here we describe a general protocol for the generation of Nanobodies to be used as crystallization chaperones for the structural investigation of diverse conformational states of flexible (membrane) proteins and complexes thereof.
Els Pardon   +9 more
semanticscholar   +8 more sources

Toll-Like Receptors: General Molecular and Structural Biology

open access: yesJournal of Immunology Research, 2021
Background/Aim. Toll-like receptors (TLRs) are pivotal biomolecules in the immune system. Today, we are all aware of the importance of TLRs in bridging innate and adaptive immune system to each other.
Payam Behzadi   +2 more
doaj   +2 more sources

THE COURSE IN GENERAL BIOLOGY [PDF]

open access: greenSchool Science and Mathematics, 1908
n ...
John M. Coulter
openalex   +4 more sources

Borges Dilemma, Fundamental Laws, and Systems Biology [PDF]

open access: yesarXiv, 2007
I reason here that the known folk law in biology that there is no general law in biology because of exceptions is false. The (quantitative) systems biology offers the potential to solve the Borges Dilemma, by transcending it. There have already a plenty of indications on this trend.
Ao, P
arxiv   +5 more sources

Development of an Online General Biology Open Educational Resource (OER) Laboratory Manual

open access: goldJournal of Microbiology & Biology Education, 2021
Currently, many academic institutions are using one or more variations of online modalities due to the COVID-19 pandemic, and science educators face a unique challenge with distance-learning laboratories.
Dmitry Y. Brogun   +3 more
doaj   +2 more sources

A family tree of Markov models in systems biology [PDF]

open access: yesIET Syst Biol. 1 (2007) 247-254, 2006
Motivated by applications in systems biology, we seek a probabilistic framework based on Markov processes to represent intracellular processes. We review the formal relationships between different stochastic models referred to in the systems biology literature. As part of this review, we present a novel derivation of the differential Chapman-Kolmogorov
Alfonsi   +33 more
arxiv   +3 more sources

A general theory for temperature-dependence in biology [PDF]

open access: greenProceedings of the National Academy of Sciences, 2021
AbstractAt present, there is no simple, complete, and first principles-based model for quantitatively describing the full range of observed biological temperature responses. Here, we derive a theory exhibiting these features based on the Eyring-Evans-Polanyi theory governing chemical reaction rates, and which is applicable across all scales from the ...
José Ignacio Arroyo   +4 more
openalex   +5 more sources

Chemoreception in the context of the general biology of ROS [PDF]

open access: greenRespiratory Physiology & Neurobiology, 2007
Superoxide anion is the most important reactive oxygen species (ROS) primarily generated in cells. The main cellular constituents with capabilities to generate superoxide anion are NADPH oxidases and mitochondrial respiratory chain. The emphasis of our article is centered in critically examining hypotheses proposing that ROS generated by NADPH oxidase ...
C. González   +8 more
openalex   +5 more sources

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