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Landscape Paradigms in Physics and Biology: Introduction and Overview [PDF]
, 1996 A brief introductory overview in general terms is given of concepts, issues and applications of the paradigm of rugged landscapes in the contexts of physics and biology.
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A framework for philosophical biology [PDF]
, 2016 Advances in biology have mostly relied on theories that were subsequently revised, expanded or eventually refuted using experimental and other means. Theoretical biology used to primarily provide a basis to rationally examine the frameworks within which biological experiments were carried out and to shed light on overlooked gaps in understanding. Today,
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Evaluating the Potential of Leading Large Language Models in Reasoning Biology Questions [PDF]
arXiv, 2023 Recent advances in Large Language Models (LLMs) have presented new opportunities for integrating Artificial General Intelligence (AGI) into biological research and education. This study evaluated the capabilities of leading LLMs, including GPT-4, GPT-3.5, PaLM2, Claude2, and SenseNova, in answering conceptual biology questions.
arxiv
Approximation of Intractable Likelihood Functions in Systems Biology via Normalizing Flows [PDF]
arXiv, 2023 Systems biology relies on mathematical models that often involve complex and intractable likelihood functions, posing challenges for efficient inference and model selection. Generative models, such as normalizing flows, have shown remarkable ability in approximating complex distributions in various domains. However, their application in systems biology
arxiv
Nontrivial quantum effects in biology: A skeptical physicists' view [PDF]
, 2007 Invited contribution to "Quantum Aspects of Life", D. Abbott Ed. (World Scientific, Singapore, 2007).
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Learning Each Others' Ropes: Negotiating interdisciplinary authenticity [PDF]
Cell Biology Education - Life Science Education 12 (June 3, 2013)
175-186, 2012 A common feature of the recent calls for reform of the undergraduate biology curriculum has been for better coordination between biology and the courses from the allied disciplines of mathematics, chemistry, and physics. Physics has lagged math and chemistry in creating new biologically oriented curricula, though much activity is now taking place and ...
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Nuovo Cimento D 20 (January 1998) 73-78, 1996 A small collection of general facts related to DNA is ...
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A. Sergi, Atti della Accademia Peloritana dei Pericolanti Vol.
LXXXVII, C1C0901001 (2009), 2009 A critical assessment of the recent developments of molecular biology is presented. The thesis that they do not lead to a conceptual understanding of life and biological systems is defended. Maturana and Varela's concept of autopoiesis is briefly sketched and its logical circularity avoided by postulating the existence of underlying {\it living ...
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A family tree of Markov models in systems biology [PDF]
IET Syst Biol. 1 (2007) 247-254, 2006 Motivated by applications in systems biology, we seek a probabilistic framework based on Markov processes to represent intracellular processes. We review the formal relationships between different stochastic models referred to in the systems biology literature. As part of this review, we present a novel derivation of the differential Chapman-Kolmogorov
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Borges Dilemma, Fundamental Laws, and Systems Biology [PDF]
arXiv, 2007 I reason here that the known folk law in biology that there is no general law in biology because of exceptions is false. The (quantitative) systems biology offers the potential to solve the Borges Dilemma, by transcending it. There have already a plenty of indications on this trend.
arxiv