A case study in model-driven synthetic biology [PDF]
We report on a case study in synthetic biology, demonstrating the modeldriven design of a self-powering electrochemical biosensor. An essential result of the design process is a general template of a biosensor, which can be instantiated to be adapted ...
Trybiło, M +5 more
core +7 more sources
Nutritional Systems Biology Modeling: From Molecular Mechanisms to Physiology [PDF]
The use of computational modeling and simulation has increased in many biological fields, but despite their potential these techniques are only marginally applied in nutritional sciences.
Ommen, Ben van +57 more
core +3 more sources
A Conserved Cell Growth Cycle Can Account for the Environmental Stress Responses of Divergent Eukaryotes [PDF]
The respiratory metabolic cycle in budding yeast (Saccharomyces cerevisiae) consists of two phases most simply defined phenomenologically: low oxygen consumption (LOC) and high oxygen consumption (HOC).
Airoldi, Edoardo| +15 more
core +1 more source
A Richer and More Diverse Future for Cell Biology [PDF]
Our vision: within the next few decades the composition of the faculty of cell biology, and of all biological science departments, will reflect the diverse composition of the graduate students in those departments.
Virginia Valian +14 more
core +1 more source
Establishment of a reverse genetics system for Schmallenberg virus, a newly emerged orthobunyavirus in Europe [PDF]
Schmallenberg virus (SBV) is a newly emerged orthobunyavirus that has caused widespread disease in cattle, sheep and goats in Europe. Like other orthobunyaviruses, SBV is characterized by a tripartite negative-sense RNA genome that encodes four ...
Szemiel, A.M. +15 more
core +1 more source
Tunicates push the limits of animal evo-devo [PDF]
The phylum to which humans belong, Chordata, takes its name from one of the major shared derived features of the group, the notochord. All chordates have a notochord, at least during embryogenesis, and there is little doubt about notochord homology at ...
David EK Ferrier +2 more
core +1 more source
The small genome segment of Bunyamwera orthobunyavirus harbours a single transcription-termination signal [PDF]
Transcription termination of the mRNA produced from the small (S) genome segment of Bunyamwera orthobunyavirus (BUNV) has previously been mapped to two cis-acting sequences located within the 5′ UTR using a virus-free replication assay.
Elliott, Richard Michael +5 more
core +1 more source
Towards molecular systems biology of gene transcription and regulation [PDF]
Ten years after the determination of the RNA polymerase 11 structure, the basic mechanism of mRNA synthesis during gene transcription is known. In the future, the initiation and regulation of transcription must be studied with a combination of structural
Cramer, P., Cramer, Patrick
core +1 more source
Multiplexed analysis of EV reveals specific biomarker composition with diagnostic impact
Multiplexed analyses of near single EVs is currently challenging. Here the authors report the method MASEV, multiplexed analysis of EVs, to interrogate thousands of individual EVs during 5 cycles of multi-channel fluorescence staining for 15 EV ...
Joshua D. Spitzberg +5 more
doaj +1 more source
THE COURSE IN GENERAL BIOLOGY [PDF]
n ...
openaire +2 more sources

