Results 41 to 50 of about 393,822 (307)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Contexts for questioning: Two zones of teaching and learning in undergraduate science [PDF]

open access: yes, 2012
This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ Springer Science+Business Media B.V.
da Silva Lopes, B   +3 more
core   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

open access: yesFEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl   +13 more
wiley   +1 more source

Biology teachers’ preferences and key factors in adopting learning technology

open access: yesJPBI (Jurnal Pendidikan Biologi Indonesia)
Technology development has changed students' characteristics and learning needs. As facilitators of student learning, teachers should be able to use learning technology effectively in their classrooms.
Ahmad Kamal Sudrajat   +2 more
doaj   +1 more source

Wildfires Risk Assessment Using Hotspot Analysis and Results Application to Wildfires Strategic Response in the Region of Tangier-Tetouan-Al Hoceima, Morocco

open access: yesFire, 2023
In recent years, changes in climate, land cover, and sociodemographic dynamics have created new challenges in wildfire management. As a result, advanced and integrated approaches in wildfire science have emerged.
Hamid Boubekraoui   +4 more
doaj   +1 more source

Developing Leadership in a National Cohort of Secondary Biology Teachers: Uses of an On-Line Course Structure to Develop Geographically Distant Professional Learning Community [PDF]

open access: yes, 2009
This report is a descriptive study of the role that on-line courses might have on the development of Professional Learning Communities (PLC’s) that support national leadership initiatives of participating high school biology teachers.
Balcerzak, P., May, V., Schaal, B.
core   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Transforming classroom practices through teachers' learning of TPACK: The case of in-service teachers at Kibasila Secondary School in Tanzania [PDF]

open access: yes, 2012
This study investigated the extent to which teachers’ learning of Technological Pedagogical Content Knowledge (TPACK) has an impact on their technology use and classroom practices.
Fisser, P.H.G.   +2 more
core   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

The complete chloroplast genome of Rubus pacificus (Rosaceae)

open access: yesMitochondrial DNA. Part B. Resources, 2022
The complete chloroplast genome of Rubus pacificus, a representative species of R. sect. Malachobatus subsect. Stipulosi, has been characterized by reference-based assembly using Illumina paired-end data.
Xian-Hua Xiong   +4 more
doaj   +1 more source

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