Results 221 to 230 of about 79,673 (289)

Antho-RFamide effect on light production in the bioluminescent sea pen Pennatula phosphorea (Octocorallia, Pennatulacea). [PDF]

J Exp Biol
Duchatelet L, Flammang P, Dupont S, Mallefet J.   +3 more
europepmc   +1 more source

A Biomimetic cRGDyk‐Engineered Platelet Nanoplatform for ACAD11 Delivery to Trigger Pyroptosis in Hepatocellular Carcinoma

Advanced Science, EarlyView.
A biomimetic platelet nanoplatform (OE‐ACAD11@R‐PLT) is developed for targeted hepatocellular carcinoma immunotherapy. By selectively delivering therapeutic plasmids, this system induces mitochondrial dysfunction and triggers robust NLRP3/Caspase‐1/GSDMD‐mediated pyroptosis in tumor cells.
Hongyi Bao, Wei Feng, Wei Zong, Yi Li, Xinyue Qin, Xinyue Wang, Yubo Yang, Guanhua Chen, Yiting Hou, Xuan Tan, Lin Chen, Ming Zhang, Feng Wang   +12 more
wiley   +1 more source

A Dual‐Delivery System Designed to Overcome EV‐Mediated Ferroptosis Resistance for Efficient Solid Tumor Therapy

Advanced Science, EarlyView.
(A) Establishment and characterization of the osteosarcoma‐targeted dual‐delivery nanoplatform mBAP1/siENO1@LNP‐OTP for simultaneous regulation of BAP1 and ENO1 in tumor cells. (B) After intravenous administration, mBAP1/siENO1@LNP‐OTP preferentially accumulates at tumor sites through OTP‐mediated targeting.
Yechao Shen, Zhenguo Cao, Zenan Wang, Liang Chen, Jiahao Zhang, Linjie Zeng, Boren Tan, Hengyuan Li, Jiashan Lai, Jiangchu Lei, Fanglu Chen, Peng Lin, Zhenxuan Shao, Zhan Wang   +13 more
wiley   +1 more source

Engineering glowing plants: recent progress and future directions for application-oriented design. [PDF]

Front Bioeng Biotechnol
Cui G.
europepmc   +1 more source

Aged ZnO Nanoparticles Promote Breast Cancer Lung Metastasis by Remodeling the Pulmonary Microenvironment Through the CXCL10/Wnt/β‐Catenin Axis

Advanced Science, EarlyView.
In summary, pulmonary exposure to ZnO NPs, particularly aged NPs, promotes breast cancer metastasis by remodelling the lung tumour microenvironment. Aged ZnO NPs enrich M2‐macrophages, MDSCs and activated CAFs to form an immunosuppressive metastatic niche. CXCL10 from these cells drives metastasis via Wnt/β‐catenin activation.
Yong Zhu, Siyu Wang, Tong Lin, Jingyi Zhang, Jingya Yang, Dixiang Kang, Wenting Zhao, Na Yu, Meimei Wang   +8 more
wiley   +1 more source

Spatial Tail Design in Ionizable Lipids Enhances the Safety and Efficacy of mRNA Delivery. [PDF]

Small Methods
Li H, Tian C, Kong W, Weiss J, Gang J, Zhong T, Ma Y, Xu J, Tai W, Zeng F, Wu S.   +10 more
europepmc   +1 more source

The Collective Power of Bacteria as a Blueprint for Emergent Intelligence

Advanced Intelligent Systems, EarlyView.
Small cells, powerful collectives. Bacteria demonstrate how sophisticated behaviors can emerge from many simple individuals working together. We explore the remarkable world of bacterial communities and the mechanisms that underpin their complex emergent behaviors, enabling impressive adaptability, robustness, and responsiveness to changing ...
Johanna A. Blee, Thomas E. Gorochowski, Sabine Hauert   +2 more
wiley   +1 more source

Reporter immunogenicity as a defined rejection antigen: a noninvasive platform for skin transplant immunobiology. [PDF]

Front Immunol
Jeffs S, Wang JS, Goud R, No J, Lorio G, Lin GH, Moon N, Tu VY, Trotter TN, Hartman ZC, Segura T.   +10 more
europepmc   +1 more source

Multimodal Assessment of Hand Hygiene Quality Using ATP Bioluminescence, Microbiological Culture, and UV-Fluorescence Digital Imaging: A Prospective Before-After Study Across Intensive Care, Hematology, and Gynecology Departments. [PDF]

J Clin Med
Radu L, Novac MB, Vasile RC, Rotaru-Zăvăleanu AD, Martin L, Stoica GA.   +5 more
europepmc   +1 more source