CTSC Confers Radioresistance in Hepatocellular Carcinoma by Regulating Myeloid-Derived Suppressor Cells. [PDF]
Xu J +5 more
europepmc +1 more source
Rational Design and Development of Organic Afterglow Nanoparticles for Image‐Guided Interventions
This review outlines the rational design, synthesis, and standardized characterization of organic afterglow nanoparticles for biomedical imaging and therapy. Mechanistic insights into chemically initiated electron exchange luminescence and reactive oxygen species‐mediated processes are connected to molecular engineering and nanoparticle fabrication ...
Asma Harun +6 more
wiley +1 more source
Hidden in the daylight: A polyphasic approach reveals two bioluminescent Mycenaceae species from Yunnan Province, China (Basidiomycota, Agaricales). [PDF]
Lu W +8 more
europepmc +1 more source
Hox Gene Variation Drives Morphological Specialization of Humpback Grouper Cromileptes altivelis
Cromileptes altivelis exhibits a distinctive “sunken head and humpback” morphology, formed through cranial remodeling. Genetic analyses identified unique amino acid variants in Hoxa7a and Hoxa10b, with functional tests confirming their role in enhancing osteoblast activity and driving cranial remodeling.
Xiaoying Cao +4 more
wiley +1 more source
Revealing vortex structure with pyrocystis lunula bioluminescence. [PDF]
Castellani L +5 more
europepmc +1 more source
Novel Bispecific Engagers Targeting the CεmX Domain of mIgE‐Expressing Cells
We developed bispecific TCE & NKCE targeting the CεmX domain of mIgE to eliminate IgE‐producing cells. Both constructs demonstrated potent, specific, dose‐dependent cytotoxicity and selective immune activation in vitro. These results highlight their promise as off‐the‐shelf, potentially curative therapeutics for IgE‐associated allergic diseases ...
Constantin Möller +16 more
wiley +1 more source
Synthetic Cells with Chemo–Optical Signaling Enable Targeted Capture and Killing of Bacteria
Wegner S +4 more
europepmc +1 more source
Divergent effects of topical deferoxamine treatment on skin and cancer cells uncovers its potential as a safe radioprotective agent in oncological applications. [PDF]
Ledwon JK +9 more
europepmc +1 more source
ABSTRACT Background Cell therapy, particularly those utilizing mesenchymal stem/stromal cells (MSCs), is gaining traction as a therapeutic option for regenerative treatment in patients with limited therapeutic options. Although the safety of MSC‐based interventions is well established, uncertainties remain regarding how genetic abnormalities and ...
Marzena Zychowicz +12 more
wiley +1 more source
Phenotypic characterization of signature-tagged mutants identifies physiological determinants of <i>Vibrio vulnificus</i> fitness. [PDF]
Yamazaki K, Kado T, Kashimoto T.
europepmc +1 more source

