Results 31 to 40 of about 73,680 (292)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
, 2019 This article summarizes the history, principles, and application of bioluminescence or “living light.” Key species are introduced including firefly (Lampyridae), luminous coelenterates and marine bacteria, and an overview of the biochemistry and ...
LJ Kricka (15776951) +3 more
core +2 more sources
Dinoflagellate bioluminescence in response to mechanical stimuli in water flows [PDF]
Nonlinear Processes in Geophysics, 2005 Bioluminescence of plankton organisms induced by water movements has long been observed and is still under investigations because of its great complexity.
A. S. Cussatlegras, P. Le Gal
doaj
Bioluminescence imaging of Chlamydia muridarum ascending infection in mice. [PDF]
PLoS ONE, 2014 Chlamydial pathogenicity in the upper genital tract relies on chlamydial ascending from the lower genital tract. To monitor chlamydial ascension, we engineered a luciferase-expressing C. muridarum.
Jessica Campbell +5 more
doaj +1 more source
Frontiers in Plant Science, 2021 Imaging technology can provide insight into biological processes governing plant-pathogen interactions. We created and used a bioluminescent strain of Xanthomonas hortorum pv.
Eduardo Bernal +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
, 2023 A. In vivo representative bioluminescence ventral view images of mice from the three treatment cohorts; control, isoflurane, and ketamine in C57BL/6 and NSG mice strains. Images are at day 14 post-injection.
Dominique Abrahams (13106815) +7 more
core +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Epidemiology, Biostatistics and Public Health, 2022 Background: Adenosine triphosphate bioluminescence produced by the firefly luciferase has been successfully introduced to verify cleaning procedures in the food industry according to the Hazard Analysis Critical Control Point program.
Daniele Domenico Raia +8 more
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source