Results 51 to 60 of about 21,813 (218)

Biomarcadores Sanguíneos em Doença de Alzheimer: Ponto de Situação e Considerações Práticas

Gazeta Médica
A doença de Alzheimer é entendida hoje como uma entidade clínico-biológica cuja caracterização deverá levar em conta a utilização de biomarcadores. Até recentemente, o uso de biomarcadores obrigava a realização de punção lombar ou à realização de PET. O
Rui Araújo, Bárbara Martins, Ana Sardoeira, Ana Gouveia   +3 more
doaj   +1 more source

Duration of Humoral and Cellular Immunity 8 Years After Administration of Reduced Doses of the 17DD-Yellow Fever Vaccine

Frontiers in Immunology, 2019
The present study aims to determine whether 17DD-YF-specific humoral and cellular immunological memory is maintained 8-years after primary vaccination with subdoses (10,447IU;3,013IU;587IU;158IU;31IU).
Ismael Artur da Costa-Rocha, Ana Carolina Campi-Azevedo, Vanessa Peruhype-Magalhães, Jordana Grazziela Coelho-dos-Reis, Jordana Grazziela Coelho-dos-Reis, Jordana Rodrigues Barbosa Fradico, Thalles Souza-Lopes, Laise Rodrigues Reis, Larissa Chaves Freire, Christiane Costa-Pereira, Juliana Vaz de Melo Mambrini, Maria de Lourdes de Sousa Maia, Sheila Maria Barbosa de Lima, Tatiana Guimarães de Noronha, Janaina Reis Xavier, Luiz Antonio Bastos Camacho, Elizabeth Maciel de Albuquerque, Roberto Henrique Guedes Farias, Thalita da Matta de Castro, Akira Homma, Alessandro Pecego Martins Romano, Carla Magda Domingues, Reinaldo de Menezes Martins, Andréa Teixeira-Carvalho, Olindo Assis Martins-Filho   +24 more
doaj   +1 more source

Screening the Community for Individuals at Clinical High Risk (CHR) for Psychosis

Early Intervention in Psychiatry, Volume 19, Issue 6, June 2025.
ABSTRACT Introduction The aim of our study was to assess the performance of the Prodromal Questionnaire‐16 (PQ‐16) and the Perceptual and Cognitive Aberrations scale (PCA) to screen for clinical high risk for psychosis (CHR) in a sample of nonhelp‐seeking subjects from São Paulo, Brazil. Methods Individuals aged 18–35 years were interviewed with the PQ‐
Alexandre Andrade Loch, Anderson Ara, Feten Fekih‐Romdhane, Leonardo Peroni de Jesus, Julio Cesar Andrade, Melina Mendonça, Maurício Henriques Serpa, Martinus Theodorus van de Bilt, Wagner Farid Gattaz   +8 more
wiley   +1 more source

A IMPORT NCIA DE BIOMARCADORES PARA DIAGNÓSTICO PRECOCE DE MIELOMA MÚLTIPLO

Hematology, Transfusion and Cell Therapy
Objetivos: O presente estudo tem como objetivo analisar a relevância dos biomarcadores no manejo do mieloma múltiplo,com a finalidade de aprimorar o diagnóstico precoce e, por conseguinte, otimizar o prognóstico dos pacientes, possibilitando intervenções
MA Simões, EG Martins, TT Monteiro, RFP Filho, KSF Araújo, GS Nobre, VD Porto, IS Sousa, RGM Araújo, LC Tavares   +9 more
doaj   +1 more source

Claw growth rates in a subset of adult, indoor, domestic cats (Felis catus)

Veterinary Dermatology, Volume 36, Issue 3, Page 362-367, June 2025.
Background – Keratinised tissues, such as nails and claws, accumulate hormones over time; the claws' hormone concentrations are being explored as potential biomarkers. Timelines for hormone deposition can be established if claw growth rates are known. Hormone concentration within cat claws has been recently evaluated, yet the growth rates of cat claws ...
Elena T. Contreras, Kate Bruner, Courtney Hegwer, Andrew Simpson   +3 more
wiley   +1 more source

Biomarcadores de exposição a chumbo

Medicina (Ribeirão Preto), 2009
O objetivo deste artigo é descrever alguns dos principais biomarcadores de exposição a chumbo, mostrando suas vantagens e limitações, assim como sua relação com exposição presente, passada ou cumulativa. Essas noções básicas são fundamentais para a compreensão dos efeitos do chumbo, da dificuldade do diagnóstico e do problema da exposição a baixas ...
Raquel Fernanda Gerlach, Soraya Cheier Dibb Gonçalves, Carolina Souza Guerra   +2 more
openaire   +3 more sources

Screening for pre‐eclampsia using pregnancy‐associated plasma protein‐A or placental growth factor measurements in blood samples collected at 8–14 weeks' gestation

Ultrasound in Obstetrics &Gynecology, Volume 65, Issue 5, Page 567-574, May 2025.
ABSTRACT Objectives To assess the value of pregnancy‐associated plasma protein‐A (PAPP‐A) in screening for preterm pre‐eclampsia (PE) (delivery < 37 weeks' gestation) measured in maternal blood samples collected before 11 weeks, and to compare the screening performance of PAPP‐A with that of placental growth factor (PlGF) from blood samples collected ...
L. Rode, A. Wright, D. Wright, M. Overgaard, L. Sperling, P. Sandager, P. Nørgaard, F. S. Jørgensen, H. Zingenberg, I. Riishede, A. Tabor, C. K. Ekelund, the PRESIDE Study Group, M. R. Andersen, L. Bathum, C. A. Juel Jensen, C. S. Knudsen, N. G. Pedersen, K. Pihl, C. Vedel, H. Skov, S. R. Wagner   +21 more
wiley   +1 more source

Biomarcadores en paciente frágil: una revisión exploratoria.

, 2022
Introducción: La fragilidad es un síndrome que aumenta la morbimortalidad en adultos mayores; además, debido a su relación con un estado proinflamatorio, múltiples biomarcadores han sido estudiados con el fin de ...
Rodrigo Bastidas, Alirio, Gutiérrez Londoño, Felipe, Ríos Barbosa, Fernando, Ospina Gómez, Sebastián, Solano González, Juan Sebastián   +4 more
core   +1 more source

Immune mediators as plasma biomarkers for identifying household contacts and classifying clinical forms and leprosy reactions

Frontiers in Immunology
The present study aimed to evaluate the performance of plasma immune mediators in classifying leprosy patients [L(PB) and L(MB), paucibacillary and multibacillary leprosy, respectively], leprosy reaction patients (T1LR and T2LR, type 1 and type 2 leprosy
Jairo Campos Carvalho, Jairo Campos Carvalho, Marcelo Antônio Pascoal-Xavier, Marcelo Antônio Pascoal-Xavier, Marcelo Grossi Araújo, Júlia Pereira Martins, Andrea Teixeira-Carvalho, Matheus de Souza Gomes, Laurence Rodrigues Amaral, Vanessa Peruhype-Magalhães, Jordana Grazziela Alves Coelho-dos-Reis, Olindo Assis Martins-Filho, Márcio Sobreira Silva Araújo   +12 more
doaj   +1 more source

Detection of human cytomegalovirus cell‐free DNA in pregnant women with symptomatically infected fetuses: proof‐of‐concept study

Ultrasound in Obstetrics &Gynecology, Volume 65, Issue 4, Page 470-477, April 2025.
ABSTRACT Objective To evaluate the presence and levels of cytomegalovirus (CMV) cell‐free DNA (cfDNA) fragments in women pregnant with a fetus with symptomatic congenital CMV (cCMV). Methods The study comprised nine women whose fetuses were diagnosed with cCMV between June 2019 and July 2024 at 20 + 4 to 34 + 1 weeks' gestation (n = 8) or neonatally (n 
B. H. W. Faas, T. Meuleman, G. Astuti, A. Reuss, K. Stol, E. A. Sistermans, J. Linthorst, E. van Leeuwen, J. Rahamat‐Langendoen, F. A. Wilmink   +9 more
wiley   +1 more source