Results 61 to 70 of about 31,122 (220)

Kynurenine pathway metabolite alterations in Down syndrome and Alzheimer's disease

Alzheimer's &Dementia, Volume 21, Issue 5, May 2025.
Abstract INTRODUCTION Down syndrome (DS) is a genetic disorder that leads to intellectual disability and accelerated aging, increasing the risk of Alzheimer's disease (AD). The pathophysiology of AD and DS is multifactorial, involving amyloid precursor protein overexpression, neuroinflammation, and oxidative stress.
Rafaela Gomes dos Reis, Monique Patricio Singulani, Orestes Vicente Forlenza, Wagner Farid Gattaz, Leda Leme Talib   +4 more
wiley   +1 more source

Biomarcadores de exposição a chumbo

Medicina (Ribeirão Preto), 2009
O objetivo deste artigo é descrever alguns dos principais biomarcadores de exposição a chumbo, mostrando suas vantagens e limitações, assim como sua relação com exposição presente, passada ou cumulativa. Essas noções básicas são fundamentais para a compreensão dos efeitos do chumbo, da dificuldade do diagnóstico e do problema da exposição a baixas ...
Raquel Fernanda Gerlach, Soraya Cheier Dibb Gonçalves, Carolina Souza Guerra   +2 more
openaire   +3 more sources

Más allá del laboratorio: biomarcadores para transformar la detección y el tratamiento del cáncer con un enfoque social: Beyond the lab: biomarkers to transform cancer detection and treatment with a social approach [PDF]

La capacidad de medir o evaluar el pronóstico de una enfermedad y, en consecuencia, orientar el tratamiento es posible gracias al desarrollo de indicadores biológicos, denominados de manera general biomarcadores.
Carrillo Tapia, Eduardo, Martínez, Orlando Ángeles, Quintas Granados, Laura Itzel   +2 more
core   +1 more source

Traditional biomarkers in narcolepsy: experience of a Brazilian sleep centre

Arquivos de Neuro-Psiquiatria, 2010
This study was thought to characterized clinical and laboratory findings of a narcoleptic patients in an out patients unit at São Paulo, Brazil. METHOD: 28 patients underwent polysomnographic recordings (PSG) and Multiple Sleep Latency Test (MSLT) were ...
Fernando Morgadinho Santos Coelho, Márcia Pradella-Hallinan, Mario Pedrazzoli, Carlos Augusto Senne Soares, Gustavo Bruniera Peres Fernandes, André Leite Gonçalves, Sergio Tufik, Lia Rita Azeredo Bittencourt   +7 more
doaj   +1 more source

Screening for pre‐eclampsia using pregnancy‐associated plasma protein‐A or placental growth factor measurements in blood samples collected at 8–14 weeks' gestation

Ultrasound in Obstetrics &Gynecology, Volume 65, Issue 5, Page 567-574, May 2025.
ABSTRACT Objectives To assess the value of pregnancy‐associated plasma protein‐A (PAPP‐A) in screening for preterm pre‐eclampsia (PE) (delivery < 37 weeks' gestation) measured in maternal blood samples collected before 11 weeks, and to compare the screening performance of PAPP‐A with that of placental growth factor (PlGF) from blood samples collected ...
L. Rode, A. Wright, D. Wright, M. Overgaard, L. Sperling, P. Sandager, P. Nørgaard, F. S. Jørgensen, H. Zingenberg, I. Riishede, A. Tabor, C. K. Ekelund, the PRESIDE Study Group, M. R. Andersen, L. Bathum, C. A. Juel Jensen, C. S. Knudsen, N. G. Pedersen, K. Pihl, C. Vedel, H. Skov, S. R. Wagner   +21 more
wiley   +1 more source

Biomarcadores oculares

, 2021
La actual revisión bibliográfica está enfocada en el uso de los biomarcadores en cuanto a las enfermedades oculares. La capacidad de estas moléculas respecto a las enfermedades varía en cuanto a, ventajas que llegan desde su detección, evaluación hasta la prevención.
openaire   +2 more sources

Interpretación de pruebas genéticas y biomarcadores en la distrofia muscular de Duchenne

Revista Ciencias de la Salud
Entre las principales alteraciones que caracterizan la distrofia muscular de Duchenne (DMD) se encuentran: daño de las fibras musculares durante la contracción, daño muscular crónico subsecuente, inflamación y posterior reemplazo de las fibras musculares
Fernando Suárez-Obando, Carolina Rivera Nieto, Norma Carolina Barajas Viracachá, Paulo César Becerra Ortiz, Edna Julieth Bobadilla-Quesada, Carlos Ernesto Bolaños Almeida, José Manuel Cañón Zambrano, Sandra Milena Castellar-Leones, Manuel Huertas Quiñones, Jenny Libeth Jurado Hernández, Juan David Lasprilla Tovar, Nicolas J. Laza Gutierrez, Isabel Londoño Ossa, Sergio Alejandro Nossa Almanza, Blair Ortiz Giraldo, Fernando Ortiz-Corredor, Sandra Yaneth Ospina Lagos, Juan Carlos Prieto, Edicson Ruiz Ospina, Felipe Ruiz-Botero, Maria Salcedo-Maldonado, Diana Pilar Soto Peña, Lina Marcela Tavera-Saldaña, María Julia Torres-Nieto, Diana Carolina Sánchez-Peñarete   +24 more
doaj   +1 more source

Detection of human cytomegalovirus cell‐free DNA in pregnant women with symptomatically infected fetuses: proof‐of‐concept study

Ultrasound in Obstetrics &Gynecology, Volume 65, Issue 4, Page 470-477, April 2025.
ABSTRACT Objective To evaluate the presence and levels of cytomegalovirus (CMV) cell‐free DNA (cfDNA) fragments in women pregnant with a fetus with symptomatic congenital CMV (cCMV). Methods The study comprised nine women whose fetuses were diagnosed with cCMV between June 2019 and July 2024 at 20 + 4 to 34 + 1 weeks' gestation (n = 8) or neonatally (n 
B. H. W. Faas, T. Meuleman, G. Astuti, A. Reuss, K. Stol, E. A. Sistermans, J. Linthorst, E. van Leeuwen, J. Rahamat‐Langendoen, F. A. Wilmink   +9 more
wiley   +1 more source

Volumen intracraneal según imágenes de tomografía axial computarizada, como biomarcador de envejecimiento cerebral

Revista Cubana de Medicina Militar, 2023
Introducción: La determinación de volúmenes de múltiples estructuras encefálicas es de gran importancia en el campo de las neurociencias, ya no solo con el objetivo de medir o detectar alteraciones estructurales, sino debido a la necesidad de realizar un
Katherine Susana Hernández Cortés, Nelsa María Sagaró del Campo, Arquímedes Montoya Pedrón   +2 more
doaj  

Cerebrospinal fluid analysis in the HIV infection and compartmentalization of HIV in the central nervous system

Arquivos de Neuro-Psiquiatria, 2015
The nervous system plays an important role in HIV infection. The purpose of this review is to discuss the indications for cerebrospinal fluid (CSF) analysis in HIV infection in clinical practice.
Sérgio Monteiro de Almeida
doaj   +1 more source