Results 101 to 110 of about 746,277 (164)

Therapeutic efficacy of a novel βIII/βIV-tubulin inhibitor (VERU-111) in pancreatic cancer

Journal of Experimental & Clinical Cancer Research, 2019
Background The management of pancreatic cancer (PanCa) is exceptionally difficult due to poor response to available therapeutic modalities. Tubulins play a major role in cell dynamics, thus are important molecular targets for cancer therapy.
Vivek K. Kashyap, Qinghui Wang, Saini Setua, Prashanth K. B. Nagesh, Neeraj Chauhan, Sonam Kumari, Pallabita Chowdhury, Duane D. Miller, Murali M. Yallapu, Wei Li, Meena Jaggi, Bilal Bin Hafeez, Subhash C. Chauhan   +12 more
doaj   +1 more source

Sedimentary biomarker and isotopic indicators of the paleoclimatic history of the Walker Lake basin, western Nevada [PDF]

, 1988
Philip A. Meyers, Larry Benson
openalex   +1 more source

Diffusion basis spectrum imaging for identifying pathologies in MS subtypes [PDF]

, 2019
Diffusion basis spectrum imaging (DBSI) combines discrete anisotropic diffusion tensors and the spectrum of isotropic diffusion tensors to model the underlying multiple sclerosis (MS) pathologies. We used clinical MS subtypes as a surrogate of underlying
Cross, Anne H, George, Ajit, Naismith, Robert T, Perantie, Dana C, Schmidt, Robert E, Shirani, Afsaneh, Song, Sheng-Kwei, Sun, Peng, Trinkaus, Kathryn   +8 more
core   +1 more source

DNA adducts as biomarkers for assessing exposure to polycyclic aromatic hydrocarbons in tissues from Xuan Wei women with high exposure to coal combustion emissions and high lung cancer mortality. [PDF]

, 1993
Judy L. Mumford, Xueming Lee, Joellen Lewtas, Tie Lan Young, Regina M. Santella   +4 more
openalex   +1 more source

ctDNA and CTCs in Liquid Biopsy – Current Status and Where We Need to Progress

Computational and Structural Biotechnology Journal, 2018
We discuss the current status of liquid biopsy and its advantages and challenges with a focus on pre-analytical sample handling, technologies and workflows. The potential of circulating tumor cells and circulating tumor DNA is pointed out and an overview
Martin H.D. Neumann, Sebastian Bender, Thomas Krahn, Thomas Schlange   +3 more
doaj  

Evaluation of the effects of acetic acid and ozone treatment on the quality of fresh-cut lotus root based on grey relational analysis

Scientific Reports
This study aimed to extend the storage time of fresh-cut lotus roots. A quantitative evaluation was conducted using the grey–correlation analysis method based on the variation–coefficient weight to observe the treatment of acetic acid (0, 2%, and 5%) and
Yongqing Zhang, Dandan Zhang, Yanfang Wu, Xiaogang Yang, Haoying Li, Quanzeng Wei, Juntao Sun, Deguo Wang   +7 more
doaj   +1 more source

Sodium-dependent phosphate transporter NaPi2b as a candidate for targeted therapy: features of structure, function, and expression

Успехи молекулярной онкологии
The sodium-dependent phosphate transporter NaPi2b is an integral membrane protein of the SLC34 phosphate transporter family and is an attractive target for precision therapy of several human diseases.
R. G. Kiyamova, R. A. Vlasenkova, L. F. Bulatova   +2 more
doaj   +1 more source

Biomarker-Guided Adaptive Enrichment Design with Threshold Detection for Clinical Trials with Time-to-Event Outcome [PDF]

arXiv
Biomarker-guided designs are increasingly used to evaluate personalized treatments based on patients' biomarker status in Phase II and III clinical trials. With adaptive enrichment, these designs can improve the efficiency of evaluating the treatment effect in biomarker-positive patients by increasing their proportion in the randomized trial.
arxiv  

Exposure of iron foundry workers to polycyclic aromatic hydrocarbons: benzo(a)pyrene-albumin adducts and 1-hydroxypyrene as biomarkers for exposure. [PDF]

, 1994
Øyvind Omland, David Sherson, Åse Marie Hansen, Torben Sigsgaard, H Autrup, E Overgaard   +5 more
openalex   +1 more source

Blood group antigens and integrins as biomarkers in head and neck cancer: Is aberrant tyrosine phosphorylation the cause of altered α6β4 integrin expression? [PDF]

, 1993
Thomas E. Carey, Thankam Nair, Catherine Chern, Monica Liebert, H. Barton Grossman, Gregory T. Wolf, Carter Van Waes   +6 more
openalex   +1 more source