Results 131 to 140 of about 2,411,306 (333)

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

The role of proline P325 residue in the recognition of the MX35 epitope of the sodium-dependent phosphate transporter NaPi2b by monoclonal antibodies in ovarian carcinoma cells

Успехи молекулярной онкологии
Introduction. One of the key components of cell membranes are membrane proteins, which provide a wide range of functions – from transport and signal transmission to coordination of intercellular interactions.
L. F. Bulatova, I. A. Slidzuk, A. V. Kilunov, V. S. Skripova, R. G. Kiyamova   +4 more
doaj   +1 more source

Comprehensive RNA Sequencing in Adenoma-Cancer Transition Identified Predictive Biomarkers and Therapeutic Targets of Human CRC [PDF]

, 2020
Mingzhe Zhu, Yanqi Dang, Zhenhua Yang, Yang Liu, Li Zhang, Yangxian Xu, Wenjun Zhou, Guang Ji   +7 more
openalex   +1 more source

Association of inflammatory biomarkers with subsequent clinical course in suspected late onset sepsis in preterm neonates [PDF]

, 2021
Şerife Kurul, Sinno H. P. Simons, Christian Ramakers, Yolanda B. de Rijke, René F. Kornelisse, Irwin Reiss, H. Rob Taal   +6 more
openalex   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Molecular characterization of breast cancer CTCs associated with brain metastasis

Nature Communications, 2017
Characterization of CTCs derived from breast cancer patients with brain metastasis (BCBM) may allow for early diagnosis of brain metastasis and/or help for treatment choice and its efficacy.
Debasish Boral, Monika Vishnoi, Haowen N. Liu, Wei Yin, Marc L. Sprouse, Antonio Scamardo, David S. Hong, Tuan Z. Tan, Jean P. Thiery, Jenny C. Chang, Dario Marchetti   +10 more
doaj   +1 more source

A New Phytochemical Screening Programme used for Crops grown with Organic and Conventional Methods [PDF]

, 2002
A broad screening programme, covering the most general phytochemical groups of compounds, was developed on the basis of Thin Layer Chromatography (TLC).
Brandt, Kirsten, Christensen, Trine F., Diedrichsen, Brigitte, Kristensen, Charlotte V., Ravn, Dr. Helle Weber   +4 more
core  

Diffusion-weighted magnetic resonance imaging as a cancer biomarker: consensus and recommendations.

Neoplasia, 2009
On May 3, 2008, a National Cancer Institute (NCI)-sponsored open consensus conference was held in Toronto, Ontario, Canada, during the 2008 International Society for Magnetic Resonance in Medicine Meeting.
A. Padhani, Guoying Liu, D. Koh, T. Chenevert, H. Thoeny, T. Takahara, A. Dzik-Jurasz, B. Ross, M. Van Cauteren, D. Collins, D. Hammoud, G. Rustin, B. Taouli, P. Choyke   +13 more
semanticscholar   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

A biomarker based on gene expression indicates plant water status in controlled and natural environments

, 2013
Plant or soil water status are required in many scientific fields to understand plant responses to drought. Because the transcriptomic response to abiotic conditions, such as water deficit, reflects plant water status, genomic tools could be used to ...
Blanchet, Nicolas, Boniface, Marie-Claude, Burger, Philippe, Casadebaig, Pierre, Debaeke, Philippe, Langlade, Nicolas B., Marchand, Gwenaëlle, Maury, Pierre, Mayjonade, Baptiste, Nambinina, Fety Andrianasolo, Varès, Didier, Vincourt, Patrick   +11 more
core   +2 more sources