Results 151 to 160 of about 1,040,935 (315)

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Biomarkers in NHL

Oncotarget, 2011
Sami N. Malek * Department of Internal Medicine, Division of Hematology and Oncology, University of Michigan, 1500 E. Medical Center Drive, Ann Arbor, MI 48109 Received: April 1, 2011; Accepted: April 1, 2011; Published: April 1, 2011; Commentary On: He J, Wu J, Jiao Y, Wagner-Johnston N, Ambinder RF, Diaz LA, Kinzler KW, Vogelstein B ...
openaire   +3 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Procalcitonin as biomarker of antibiotic effectivity in communityacquired pneumonia [PDF]

, 2015
Major therapy for community-acquired pneumonia (CAP) is antibiotics. Procalcitonin used as the measure of antibioticseffectiveness. Procalcitonin is specific biomarker that elevates in acute bacterial infection.
Samirah, -, Ana Khusnul Faizah, -, Winariani, -, Yulistiani, -   +3 more
core  

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Proteoglycan 4 is a diagnostic biomarker for COPD

, 2015
Kang-Yun Lee,1,2 Hsiao-Chi Chuang,1,3 Tzu-Tao Chen,1 Wen-Te Liu,1,3 Chien-Ling Su,1,3 Po-Hao Feng,1,2 Ling-Ling Chiang,1,3 Mauo-Ying Bien,3,4 Shu-Chuan Ho3 1Division of Pulmonary Medicine, Department of Internal Medicine, Shuang Ho Hospital, Taipei ...
Su CL, Ho SC, Bien MY, Liu WT, Chen TT, Feng PH, Lee KY, Chuang HC, Chiang LL   +8 more
core  

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Biomarker-Guided Versus Guideline-Based Treatment of Patients With Heart Failure: Results From BIOSTAT-CHF

, 2018
Background: Heart failure guidelines recommend up-titration of angiotensin-converting enzyme (ACE) inhibitor/angiotensin receptor blockers (ARBs), beta-blockers, and mineralocorticoid receptor antagonists (MRAs) to doses used in randomized clinical ...
M. Metra (6176873), S. D. Anker (7604402), A. A. Voors (7594622), D. J. van Veldhuisen (7594628), Leong L. Ng (7162769), Nilesh J. Samani (7579793), C. C. Lang (7735544), G. Filippatos (7750994), H. L. Hillege (7594619), F. Zannad (7750988), A. H. Zwinderman (3801265), P. van der Harst (7594607), J. M. Ter Maaten (7750991), K. Dickstein (7750997), B. Demissei (7750985), J. G. Cleland (7751000), W. Ouwerkerk (7750982), P. Ponikowski (7604393)   +17 more
core  

Serum Periostin is Able to Stratify Type 2-Dominant Ulcerative Colitis

Background: Ulcerative colitis (UC) is a heterogeneous disease composed of different endotypes. It is important to develop useful biomarkers for endotyping UC; however, available biomarkers are insufficient.
Sakata, Yasuhisa, Akutagawa, Takashi, Aishima, Shinichi, Nanri, Yasuhiro, Tsuruoka, Nanae, Esaki, Motohiro, Conway, Simon, Kawaguchi, Atsushi, Nunomura, Satoshi, Yokomizo, Kanako, Izuhara, Kenji, Takedomi, Hironobu, Honda, Yuko   +12 more
core   +1 more source