Results 11 to 20 of about 2,295,331 (380)
A biomarker that identifies senescent human cells in culture and in aging skin in vivo. [PDF]
Goberdhan P. Dimri+9 more
openalex +2 more sources
Haptoglobin as a Biomarker [PDF]
Haptoglobin (Hp) is a blood plasma glycoprotein that binds free hemoglobin (Hb) and plays a critical role in tissue protection and the prevention of oxidative damage. In addition, it has a number of regulatory functions. Haptoglobin is an acute phase protein, its concentration in plasma changes in pathology, and the test for its concentration is ...
O. K. Legina, S. N. Naryzny
openaire +4 more sources
Biomarkers are characteristics objectively measured and evaluated as indicators of: normal biologic processes, pathogenic processes, or pharmacologic response(s) to a therapeutic intervention. In environmental research and risk assessment, biomarkers are frequently referred to as indicators of human or environmental hazards.
Harmony, Larson+3 more
+7 more sources
DunedinPACE, a DNA methylation biomarker of the pace of aging
Background: Measures to quantify changes in the pace of biological aging in response to intervention are needed to evaluate geroprotective interventions for humans.
Daniel W Belsky+19 more
semanticscholar +1 more source
Biomarkers of Cholestasis [PDF]
Cholestasis is a major pathological manifestation, often resulting in detrimental liver conditions, which occurs in a variety of indications collectively termed cholestatic liver diseases. The frequent asymptomatic character and complexity of cholestasis, together with the lack of a straightforward biomarker, hampers early detection and treatment of ...
Pieters, Alanah+5 more
openaire +4 more sources
The focus of this Special Issue on Biomedicines is on the value of “Biomarkers in Pain” from a broad perspective [...]
Anders Larsson+2 more
openaire +5 more sources
Imaging Biomarkers or Biomarker Imaging? [PDF]
Since biomarker imaging is traditionally understood as imaging of molecular probes, we highly recommend to avoid any confusion with the previously defined term “imaging biomarkers” and, therefore, only use “molecular probe imaging (MPI)” in that context. Molecular probes (MPs) comprise all kinds of molecules administered to an organism which inherently
Markus Mitterhauser, Wolfgang Wadsak
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Plasma p-tau231: a new biomarker for incipient Alzheimer’s disease pathology
The quantification of phosphorylated tau in biofluids, either cerebrospinal fluid (CSF) or plasma, has shown great promise in detecting Alzheimer’s disease (AD) pathophysiology.
N. Ashton+14 more
semanticscholar +1 more source
Biomarkers are tumour- or host-related factors that correlate with tumour biological behaviour and patient prognosis. High-throughput analytical techniques--DNA and RNA microarrays--have identified numerous possible biomarkers, but their relevance to melanoma progression, clinical outcome and the selection of optimal treatment strategies still needs to
Gogas, H.+7 more
openaire +3 more sources
Calprotectin: from biomarker to biological function
The incidence of inflammatory bowel diseases (IBD) emerged with Westernisation of dietary habits worldwide. Crohn’s disease and ulcerative colitis are chronic debilitating conditions that afflict individuals with substantial morbidity and challenge ...
A. Jukic+4 more
semanticscholar +1 more source