Results 21 to 30 of about 1,046,417 (216)
Proteomes, 2018 Diabetic mellitus (DM) is a disease that affects glucose homeostasis and causes complications, such as diabetic nephropathy (DN). For early diagnosis of DN, microalbuminuria is currently one of the most frequently used biomarkers.
Yoshitoshi Hirao +8 more
doaj +1 more source
ERJ Open Research, 2021 Introduction COPD exacerbations are heterogeneous and can be triggered by bacterial, viral, or noninfectious insults. Exacerbations are also heterogeneous in neutrophilic or eosinophilic inflammatory responses.
Arindam Chakrabarti +13 more
doaj +1 more source
A targeted solution for estimating the cell-type composition of bulk samples
BMC Bioinformatics, 2021 Background To avoid false-positive findings and detect cell-type specific associations in methylation and transcription investigations with bulk samples, it is critical to know the proportions of the major cell-types.
Edwin J. C. G. van den Oord +4 more
doaj +1 more source
Journal for ImmunoTherapy of Cancer, 2019 Background Metastatic TNBC (mTNBC) has a poor prognosis and few treatment options. The anti-PD-L1 antibody atezolizumab demonstrated clinical activity in mTNBC patients with PD-L1-positive tumor-infiltrating immune cells.
Luciana Molinero +9 more
doaj +1 more source
Journal of the Advanced Practitioner in Oncology, 2020 This JADPRO Live session tested attendees' knowledge on biomarkers and their use in determining targeted therapy for certain tumor types, key assays used to measure common biomarkers, and guideline-endorsed biomarker testing recommendations.
Held, Lauren +2 more
openaire +3 more sources
Quantitative Comparison of Conventional and t-SNE-guided Gating Analyses
Frontiers in Immunology, 2019 Dimensionality reduction using the t-Distributed Stochastic Neighbor Embedding (t-SNE) algorithm has emerged as a popular tool for visualizing high-parameter single-cell data.
Shadi Toghi Eshghi +8 more
doaj +1 more source
Immunologic Biomarkers and Biomarkers for Immunotherapies in Gastrointestinal Cancer [PDF]
Visceral Medicine, 2019 Gastrointestinal (GI) cancers contribute significantly to the worldwide cancer burden. Pathologic evaluation is indispensable for the estimation of prognosis and therapeutic strategy. At present, immunotherapies are evolving into efficient therapeutic approaches, which are accompanied by the need for biomarkers to predict therapy response.
Martin, Benedikt, Märkl, Bruno
openaire +3 more sources
BJPsych Open, 2023 Summary Dissociative symptoms present transdiagnostically and are related to poor clinical outcome. Research into the biological correlates of dissociation remains limited. This editorial summarises and discusses papers from this themed series of BJPsych Open that contribute to unravelling the biological correlates of dissociative symptomatology ...
Antje A. T. S. Reinders +2 more
openaire +4 more sources
Enhancing sepsis biomarker development: key considerations from public and private perspectives [PDF]
Implementation of biomarkers in sepsis and septic shock in emergency situations, remains highly challenging. This viewpoint arose from a public–private 3-day workshop aiming to facilitate the transition of sepsis biomarkers into clinical practice.
Rodriguez-Manzano, J +21 more
core +1 more source
Urinary proteomics to support diagnosis of stroke [PDF]
, 2012 Accurate diagnosis in suspected ischaemic stroke can be difficult. We explored the urinary proteome in patients with stroke (n = 69), compared to controls (n = 33), and developed a biomarker model for the diagnosis of stroke.
Mischak, H. +14 more
core +1 more source