Results 21 to 30 of about 2,295,331 (380)
Clinical Chemistry and Laboratory Medicine, 2020 Background As coronavirus disease 2019 (COVID-19) pandemic rages on, there is urgent need for identification of clinical and laboratory predictors for progression towards severe and fatal forms of this illness.
B. Henry +4 more
semanticscholar +1 more source
The application of Aptamer in biomarker discovery
Biomarker Research, 2023 Biomarkers are detectable molecules that can reflect specific physiological states of cells, organs, and organisms and therefore be regarded as indicators for specific diseases. And the discovery of biomarkers plays an essential role in cancer management
Yongshu Li +11 more
semanticscholar +1 more source
Biomarker modeling of Alzheimer’s disease using PET-based Braak staging
Nature Aging, 2022 Gold-standard diagnosis of Alzheimer’s disease (AD) relies on histopathological staging systems. Using the topographical information from [18F]MK6240 tau positron-emission tomography (PET), we applied the Braak tau staging system to 324 living ...
J. Therriault +21 more
semanticscholar +1 more source
BioMed Research International, 2014 Bloodstream infections are a major concern because of high levels of antibiotic consumption and of the increasing prevalence of antimicrobial resistance. Bacteraemia is identified in a small percentage of patients with signs and symptoms of sepsis. Biomarkers are widely used in clinical practice and they are useful for monitoring the infectious process.
Henriquez-Camacho, Cesar, Losa, Juan
openaire +4 more sources
Frontiers in Psychiatry, 2014 Autism spectrum disorders (ASDs) are complex, heterogeneous disorders caused by an interaction between genetic vulnerability and environmental factors. In an effort to better target the underlying roots of ASD for diagnosis and treatment, efforts to identify reliable biomarkers in genetics, neuroimaging, gene expression, and measures of the body's ...
Goldani, Andre AS +4 more
openaire +6 more sources
Metagenomic biomarker discovery and explanation
Genome Biology, 2011 This study describes and validates a new method for metagenomic biomarker discovery by way of class comparison, tests of biological consistency and effect size estimation.
N. Segata +6 more
semanticscholar +1 more source
An epigenetic biomarker of aging for lifespan and healthspan
bioRxiv, 2018 Identifying reliable biomarkers of aging is a major goal in geroscience. While the first generation of epigenetic biomarkers of aging were developed using chronological age as a surrogate for biological age, we hypothesized that incorporation of ...
M. Levine +17 more
semanticscholar +1 more source
Disease Knowledge Transfer across Neurodegenerative Diseases [PDF]
, 2019 We introduce Disease Knowledge Transfer (DKT), a novel technique for transferring biomarker information between related neurodegenerative diseases. DKT infers robust multimodal biomarker trajectories in rare neurodegenerative diseases even when only ...
Alexander, Daniel C. +10 more
core +3 more sources
Clinical Proteomics, 2018 Advances in the field of targeted proteomics and mass spectrometry have significantly improved assay sensitivity and multiplexing capacity. The high-throughput nature of targeted proteomics experiments has increased the rate of data production, which ...
Shadi Toghi Eshghi +2 more
doaj +1 more source
Identification of genetic variants related to metabolic syndrome by next-generation sequencing
Diabetology & Metabolic Syndrome, 2022 Background Metabolic syndrome (MetS) is a cluster of conditions associated with glucose intolerance, hypertension, abdominal obesity, dyslipidemia, and insulin resistance that increase the risk of cardiovascular diseases (CVD) and type 2 diabetes (T2D ...
Sanghoo Lee +8 more
doaj +1 more source