Results 1 to 10 of about 3,901,828 (357)
An In Vivo Platform for Tumor Biomarker Assessment [PDF]
PLoS ONE, 2011 Tumor biomarkers provide a quantitative tool for following tumor progression and response to therapy. However, investigations of clinically useful tumor biomarkers are time-consuming, costly, and limited by patient and tumor heterogeneity.
Adusumilli, Prasad S. +8 more
core +7 more sources
ABCS Health Sciences, 2023 Introduction: Gastric cancer (GC) is the fifth most diagnosed neoplasia and the third leading cause of cancer-related deaths. A substantial number of patients exhibit an advanced GC stage once diagnosed.
Marcos Vinicius Rossetto +4 more
doaj +3 more sources
Breast Cancer Research, 2021 Background Following the PALOMA-3 study results, the combination of palbociclib, a CDK4/6 inhibitor, with fulvestrant, a selective estrogen receptor degrader, has become a standard therapy in women with estrogen receptor-positive (ER+) HER2-negative ...
Lauren Darrigues +14 more
doaj +1 more source
Metabolism and signaling crosstalk in glioblastoma progression and therapy resistance
Molecular Oncology, EarlyView., 2023 Glioblastoma is one of the most lethal human cancers with no effective treatment nowadays. Here, we review the increasing amount of evidence supporting the connection between cell signaling deregulation and metabolic reprogramming as a key event in glioblastoma resistance to cancer therapy.
Laura Zarzuela +2 more
wiley +1 more source
Biomarkers of Tumor Metastasis and Invasiveness
Cancers, 2023 The identification of proteins as new cancer diagnostic and prognostic biomarkers continues to attract considerable attention in the oncology literature, especially in the context of invasion and metastasis activation process [...]
Daniel L. Pouliquen +1 more
openaire +4 more sources
Scientific Reports, 2023 Renal cancer cells constitute a paradigm of tumor cells with a glycolytic reprogramming which drives metabolic alterations favouring cell survival and transformation.
Caroline E. Nunes-Xavier +10 more
doaj +1 more source
Frontiers in Oncology, 2022 BackgroundPyruvate dehydrogenase (PDH) complex converts pyruvate into acetyl-CoA by pyruvate decarboxylation, which drives energy metabolism during cell growth, including prostate cancer (PCa) cell growth.
Caroline E. Nunes-Xavier +11 more
doaj +1 more source
Frontiers in Immunology, 2022 Immunoglobulin M (IgM) autoantibodies, as the early appearing antibodies in humoral immunity when stimulated by antigens, might be excellent biomarkers for the early detection of lung cancer (LC).
Xue Zhang +19 more
doaj +1 more source
Biomarkers in Neuroendocrine Tumors [PDF]
JOP : Journal of the pancreas, 2013 Neuroendocrine tumors are a heterogeneous group of tumors with cells of neuroendocrine differentiation that arise from diverse anatomic sites with varying morphologic and clinical features. Since the natural history and prognosis varies widely between individual neuroendocrine tumor types, there is a critical need to identify accurate prognostic and ...
Marvin Duque +3 more
openaire +2 more sources
npj Breast Cancer, 2021 Circulating tumor cells (CTCs) and circulating tumor DNA (ctDNA) are two cancer-derived blood biomarkers that inform on patient prognosis and treatment efficacy in breast cancer.
Amanda Bortolini Silveira +24 more
doaj +1 more source