Results 41 to 50 of about 2,113,927 (314)
Plasma protein profiling reveals protein clusters related to BMI and insulin levels in middle-aged overweight subjects [PDF]
Biomarkers that allow detection of the onset of disease are of high interest since early detection would allow intervening with lifestyle and nutritional changes before the disease is manifested and pharmacological therapy is required. Our study aimed to
Edith J M Feskens +43 more
core +2 more sources
Breast fine-needle aspiration cytology in the era of core-needle biopsy: what is its role? [PDF]
Fine-needle aspiration cytology (FNAC) has long been recognized as a minimally invasive, cost-effective, and reliable diagnostic tool for breast lesions.
Ahrong Kim, Hyun Jung Lee, Jee Yeon Kim
doaj +1 more source
Dissecting the Role of AXL in Cancer Immune Escape and Resistance to Immune Checkpoint Inhibition
The development and implementation of Immune Checkpoint Inhibitors (ICI) in clinical oncology have significantly improved the survival of a subset of cancer patients with metastatic disease previously considered uniformly lethal.
Agnete S. T. Engelsen +14 more
doaj +1 more source
The Role of CTCs as Tumor Biomarkers
Detection of Circulating Tumor Cells (CTCs) in peripheral blood can serve as a "liquid biopsy" approach and as a source of valuable tumor markers. CTCs are rare, and thus their detection, enumeration and molecular characterization are very challenging.
Lianidou, E.S., Markou, A., Strati, A.
openaire +3 more sources
KCNB1 GENE POLYMORPHISMS AND RELATED INDEL AS PREDICTOR BIOMARKERS OF TREATMENT RESPONSE FOR COLORECTAL CANCER – TOWARD A PERSONALIZED MEDICINE [PDF]
The KCNB1 gene variants were differentially associated with cancers. However, their association with colorectal cancer has not yet been explored. We investigated the contribution of the KCNB1 gene variants rs3331, rs1051295, and indel (insertion ...
Kraiem, Hazar +11 more
core +1 more source
This study aimed to differentiate isocitrate dehydrogenase (IDH) mutation status with the voxel-wise clustering method of multiparametric magnetic resonance imaging (MRI) and to discover biological underpinnings of the clusters.
Akifumi Hagiwara +13 more
doaj +1 more source
The association between CTSZ methylation in peripheral blood and breast cancer in Chinese women
PurposePrevious studies have shown that DNA methylation in peripheral blood may be associated with breast cancer (BC). To explore the association between the methylation level of the Cathepsin Z (CTSZ) gene in peripheral blood and BC, we conducted a case–
Jinyu Li +18 more
doaj +1 more source
Biomarkers in Pancreatic Neuroendocrine Tumors
The aim of biomarkers is to identify patients most likely to benefit from a therapeutic strategy. Pancreatic neuroendocrine tumors are rare neoplasms that arise in the endocrine tissues of the pancreas. Pancreatic neuroendocrine tumors represent 3% of primary pancreatic neoplasms and their incidence has risen.
Maria Serafeim, Theochari +2 more
openaire +2 more sources
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Next-Generation Biomarkers for Cholangiocarcinoma
The increasing mortality rates of cholangiocarcinoma (CCA) registered during the last decades are, at least in part, a result of the lack of accurate non-invasive biomarkers for early disease diagnosis, making extremely challenging the identification of ...
Valle, Juan +11 more
core +1 more source

