Results 11 to 20 of about 3,850,355 (295)
Biomarkers of tumor invasiveness in proteomics (Review)
Over the past two decades, quantitative proteomics has emerged as an important tool for deciphering the complex molecular events involved in cancers.
D. Pouliquen+3 more
semanticscholar +7 more sources
Biomarkers in Neuroendocrine Tumors [PDF]
Neuroendocrine tumors are a heterogeneous group of tumors with cells of neuroendocrine differentiation that arise from diverse anatomic sites with varying morphologic and clinical features. Since the natural history and prognosis varies widely between individual neuroendocrine tumor types, there is a critical need to identify accurate prognostic and ...
Marvin Duque+3 more
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Circulating tumor cells (CTCs) and circulating tumor DNA (ctDNA) are two cancer-derived blood biomarkers that inform on patient prognosis and treatment efficacy in breast cancer.
Amanda Bortolini Silveira+24 more
doaj +1 more source
Colorectal cancer (CRC) is a major contributor to cancer-associated morbidity worldwide and over one-third of CRC is located in the rectum. Neoadjuvant chemoradiotherapy (nCRT) followed by surgical resection is commonly applied to treat locally advanced ...
Moying Li+7 more
semanticscholar +1 more source
Biomarkers of Pediatric Brain Tumors [PDF]
Background and Need for Novel Biomarkers: Brain tumors are the leading cause of death by solid tumors in children. Although improvements have been made in their radiological detection and treatment, our capacity to promptly diagnose pediatric brain tumors in their early stages remains limited. This contrasts several other cancers where serum biomarkers
Mark D Russell+3 more
openaire +5 more sources
The environmental and metabolic pressures in the tumor microenvironment (TME) play a key role in molding tumor development by impacting the stromal and immune cell fractions, TME composition and activation.
R. Abou Khouzam+7 more
semanticscholar +1 more source
Translational progress on tumor biomarkers [PDF]
AbstractThere is an urgent need to apply basic research achievements to the clinic. In particular, mechanistic studies should be developed by bench researchers, depending upon clinical demands, in order to improve the survival and quality of life of cancer patients.
Qian Liu+12 more
openaire +3 more sources
Molecular and Circulating Biomarkers of Brain Tumors [PDF]
Brain tumors are the most common malignant primary intracranial tumors of the central nervous system. They are often recognized too late for successful therapy. Minimally invasive methods are needed to establish a diagnosis or monitor the response to treatment of CNS tumors. Brain tumors release molecular information into the circulation.
Wojciech Jelski, Barbara Mroczko
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A DNA methylation-based liquid biopsy for triple-negative breast cancer
Here, we present a next-generation sequencing (NGS) methylation-based blood test called methylation DETEction of Circulating Tumour DNA (mDETECT) designed for the optimal detection and monitoring of metastatic triple-negative breast cancer (TNBC).
Katrina Cristall+8 more
doaj +1 more source
Imaging biomarkers for evaluating tumor response: RECIST and beyond
Response Evaluation Criteria in Solid Tumors (RECIST) is the gold standard for assessment of treatment response in solid tumors. Morphologic change of tumor size evaluated by RECIST is often correlated with survival length and has been considered as a ...
Ching-Chung Ko, L. Yeh, Y. Kuo, J. Chen
semanticscholar +1 more source