Results 251 to 260 of about 4,189,421 (356)

The value of circulating methylated septin 9 in the diagnosis and prognostic assessment of gastric cancer. [PDF]

Discov Oncol
Ni J, Hao X, Wu Y, Yu X, Liu H, Mo X, Lin Q.   +6 more
europepmc   +1 more source

Endocytic Programming via Porous Silicon Nanoparticles Enhances TLR4 Nanoagonist Potency for Macrophage‐Mediated Immunotherapy

Advanced Functional Materials, EarlyView.
Porous silicon nanoparticles (PSiNPs) reprogram macrophage endocytosis of manganese@albumin‐based TLR4 nanoagonists, driving TRIF‐biased TLR4 signaling, eliciting robust proinflammatory responses, and potentiating macrophage‐mediated immunotherapeutic effects against NSCLC.
Xiaomei Zhang, Huiying Li, Shuodan Huang, Linxuan Zhang, Yan Gao, Ruoran Wang, Xiaoyu Wang, Hélder A. Santos, Zhenyu Yin, Bing Xia   +9 more
wiley   +1 more source

Associations of Biomarkers of Systemic Inflammation, Angiogenesis, and Cell-to-Cell Adhesion With Tumor Budding Among Early-Onset and Later-Onset Colorectal Cancer Patients. [PDF]

Cancer Med
Hausmann O, Schobert PP, Ose J, Himbert C, Pletneva M, Jedrzkiewicz J, Nguyen A, Lin T, Warby CA, Hardikar S, Peoples AR, Strehli I, Huang LC, Cohan JN, Pickron B, Scaife C, Li CI, Grady WM, Shibata D, Toriola AT, Schneider M, Figueiredo JC, Siegel EM, Gigic B, Herzig S, Ilozumba MN, Ulrich CM.   +26 more
europepmc   +1 more source

Transducer Materials Mediated Deep Brain Stimulation in Neurological Disorders

Advanced Functional Materials, EarlyView.
This review discusses advanced transducer materials for improving deep brain stimulation (DBS) in neurological disorders. These materials respond to light, ultrasound, or magnetic fields, enabling precise, less invasive neuromodulation. Their stimulus‐responsive properties enhance neural control and adaptive therapy, paving the way for next‐generation ...
Di Zhao, Zhengyang Cao, Guangjun Zhong, Limin Shi, Junxia Xie, Jianhua Hao   +5 more
wiley   +1 more source

Uncovering the Tumorigenic Blueprint of PFOS and PFOA Through Multi-Organ Transcriptomic Analysis of Biomarkers, Mechanisms, and Therapeutic Targets. [PDF]

Curr Issues Mol Biol
Mathur K, Khaliq A, Park S, Chu N, Burra VM, Kanukolanu N, Costello E, Dakshanamurthy S.   +7 more
europepmc   +1 more source

FeDSNP‐Pa Nanoassemblies: A Triple‐Action Therapeutic Strategy Targeting Oxidative Stress, Inflammation, and Pyroptosis for Retinal Ganglion Cell Protection in Glaucoma

Advanced Functional Materials, EarlyView.
FeDSNP‐Pa, a metallized nanoparticle loaded with sodium pyruvate (Pa), exerts triple therapeutic effects by scavenging reactive oxygen species (ROS), suppressing inflammatory responses, and inhibiting pyroptosis signaling pathways. This multifunctional neuroprotective strategy protecting retinal ganglion cells (RGCs) from elevated intraocular pressure ...
Yukun Wu, Xue Li, Tong Wu, Dan Ji, Yugang Bai, Xuezhi Zhou   +5 more
wiley   +1 more source

Extracellular Vesicles as Novel Biomarkers for Tumor Association in Intermediate-Risk Paraneoplastic Neurologic Syndromes. [PDF]

Neurol Neuroimmunol Neuroinflamm
Torres Iglesias G, Chavarría-Miranda A, López-Molina M, Del Fresno C, Mata-Martínez P, Nozal P, Chico-Garcia JL, Fernández-Fournier M, Lacruz Ballester L, Sanchez D, Montero-Calle A, Barderas R, Bravo S, Puertas I, York E, Díez-Tejedor E, Gutiérrez-Fernández M, Otero-Ortega L.   +17 more
europepmc   +1 more source

A randomized controlled trial of the tumor necrosis factor antagonist infliximab for treatment-resistant depression: the role of baseline inflammatory biomarkers.

JAMA psychiatry, 2013
C. Raison, R. Rutherford, B. Woolwine, C. Shuo, P. Schettler, D. F. Drake, E. Haroon, Andrew H. Miller   +7 more
semanticscholar   +1 more source

From Exciton Dynamics to Cell Fate: A Carbon Dot Based NIR Photocatalytic Platform for Pyroptosis via Self‐Trapped Excitons

Advanced Functional Materials, EarlyView.
A facile and effective method to boost NIR light induced photocatalysis based on nontoxic NIR emissive carbon dots (nir‐CDs) via Self‐trapped excitons, showing that both O2− • and •OH can be generated from nir‐CDs under NIR laser irradiation. Abstract Near‐infrared (NIR) light‐triggered photocatalytic therapy remains a critical challenge in efficient ...
Qingcheng Wang, Quansheng Cheng, Bingzhe Wang, Tesen Zhang, Yupeng Liu, Ruifeng Zheng, Shi Chen, Guichuan Xing, Songnan Qu   +8 more
wiley   +1 more source

How Advanced Are Extracellular Vesicles in Renal Cell Carcinoma? For Diagnostic and Therapeutic Frontiers. [PDF]

Int J Nanomedicine
Zhou M, Wang L, Yu B, He J, Zhang J, Liu Z, Chen P, Ouyang C, Chen Z.   +8 more
europepmc   +1 more source