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Biomarkers of neuroendocrine tumors
Annales de biologie clinique, 2016Neuroendocrine tumors (NET) are rare heterogenous tumors which prevalence is increasing. Their features vary by anatomical location, functionality and hormonal production. Their management needs a multidisciplinary approach. Functional tumors develop characteristic clinical syndromes in contrast to non-functional tumors that are diagnosed fortuitously ...
Michèle, d'Herbomez +5 more
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International Journal of Oncology, 1996
Despite advances and improvements in diagnosis and treatment of upper aerodigestive tumors including head and neck and lung cancers, the overall survival rate of these patients remains poor. Prevention, early diagnosis, and novel therapy are under active investigation to improve the outcome of the diseases.
D, Shin, W, Hong
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Despite advances and improvements in diagnosis and treatment of upper aerodigestive tumors including head and neck and lung cancers, the overall survival rate of these patients remains poor. Prevention, early diagnosis, and novel therapy are under active investigation to improve the outcome of the diseases.
D, Shin, W, Hong
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MRI biomarkers in osseous tumors
Journal of Magnetic Resonance Imaging, 2019Although radiography continues to play a critical role in osseous tumor assessment, there have been remarkable advances in cross‐sectional imaging. MRI has taken a lead in this assessment due to high tissue contrast and spatial resolution, which are well suited for bone lesion assessment.
Takeshi Fukuda +4 more
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Survivin: A promising tumor biomarker
Cancer Letters, 2007Survivin is a 16.5 kDa protein overexpressed in almost all malignancies but rarely detected in normal differentiated adult tissues. Functionally, survivin has been shown to inhibit apoptosis, promote cell proliferation and enhance angiogenesis. Consistent with its role in these processes, survivin has been shown to play a key role in cancer progression.
Michael J, Duffy +4 more
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Urinary Biomarkers in Tumors: An Overview
2021Recent reports suggest that urine is a useful noninvasive tool for the identification of urogenital tumors, including bladder, prostate, kidney, and other nonurological cancers. As a liquid biopsy, urine represents an important source for the improvement of new promising biomarkers, a suitable tool to identify indolent cancer and avoid overtreatment ...
Ilaria, Cimmino +2 more
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2007
This chapter describes the key elements in tumor biomarker development toward clinical use. In particular, it focuses on the analytical aspects of assay development and how to implement new tumor biomarkers in the clinical setting.
Nils Brünner +5 more
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This chapter describes the key elements in tumor biomarker development toward clinical use. In particular, it focuses on the analytical aspects of assay development and how to implement new tumor biomarkers in the clinical setting.
Nils Brünner +5 more
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Machine Learning & Molecular Radiation Tumor Biomarkers
Seminars in Radiation Oncology, 2023Developing radiation tumor biomarkers that can guide personalized radiotherapy clinical decision making is a critical goal in the effort towards precision cancer medicine. High-throughput molecular assays paired with modern computational techniques have the potential to identify individual tumor-specific signatures and create tools that can help ...
Nicholas R, Rydzewski +6 more
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Tumor biomarkers: PSA and beyond
Clinical Chemistry and Laboratory Medicine (CCLM), 2012Laboratory medicine plays an increasingly important role in the management of cancer patients (1, 2) . In none of the tumors has the advent of biomarkers changed the treatment in a more fundamental way than the introduction of prostate specifi c antigen (PSA) which has virtually transformed the management of prostate cancer.
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MicroRNAs as Biomarkers in Pituitary Tumors
Neurosurgery, 2014The use of extracellular microRNAs (miRNAs) as circulating biomarkers is currently leading to relevant advances in the diagnosis and assessment of prognosis of several diseases. Specific miRNAs have also been shown to play a role in the pathophysiology of many neoplastic and non-neoplastic diseases.
Antonio, Di Ieva +8 more
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