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MRI biomarkers in osseous tumors
Journal of Magnetic Resonance Imaging, 2019Although radiography continues to play a critical role in osseous tumor assessment, there have been remarkable advances in cross‐sectional imaging. MRI has taken a lead in this assessment due to high tissue contrast and spatial resolution, which are well suited for bone lesion assessment.
Takeshi Fukuda +4 more
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MicroRNAs as Biomarkers in Pituitary Tumors
Neurosurgery, 2014The use of extracellular microRNAs (miRNAs) as circulating biomarkers is currently leading to relevant advances in the diagnosis and assessment of prognosis of several diseases. Specific miRNAs have also been shown to play a role in the pathophysiology of many neoplastic and non-neoplastic diseases.
Antonio, Di Ieva +8 more
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Survivin: A promising tumor biomarker
Cancer Letters, 2007Survivin is a 16.5 kDa protein overexpressed in almost all malignancies but rarely detected in normal differentiated adult tissues. Functionally, survivin has been shown to inhibit apoptosis, promote cell proliferation and enhance angiogenesis. Consistent with its role in these processes, survivin has been shown to play a key role in cancer progression.
Michael J, Duffy +4 more
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Tumor biomarkers: PSA and beyond
Clinical Chemistry and Laboratory Medicine (CCLM), 2012Laboratory medicine plays an increasingly important role in the management of cancer patients (1, 2) . In none of the tumors has the advent of biomarkers changed the treatment in a more fundamental way than the introduction of prostate specifi c antigen (PSA) which has virtually transformed the management of prostate cancer.
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Biomarkers in Gynecologic Tumors
2022Gynecologic malignancies are one of the most frequent cancers amongst women. Biomarkers are crucial for the differential diagnosis of adnexal masses; however, their potential for diagnosis is limited. In the era of difficulty in ovarian cancer screening, novel biomarkers are defined, but CA125 still remains the most valuable one. Circulating tumor DNAs,
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2007
This chapter describes the key elements in tumor biomarker development toward clinical use. In particular, it focuses on the analytical aspects of assay development and how to implement new tumor biomarkers in the clinical setting.
Nils Brünner +5 more
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This chapter describes the key elements in tumor biomarker development toward clinical use. In particular, it focuses on the analytical aspects of assay development and how to implement new tumor biomarkers in the clinical setting.
Nils Brünner +5 more
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Imaging of Integrins as Biomarkers for Tumor Angiogenesis
Current Pharmaceutical Design, 2008The integrin family plays important roles during tumor angiogenesis, the formation of new blood vessels from pre-existing vasculature. Traditional structural and functional imaging techniques are not sufficient for early lesion detection, patient stratification, or monitoring the therapeutic efficacy against cancer. Molecular imaging, the visualization,
Weibo, Cai, Gang, Niu, Xiaoyuan, Chen
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Circulating microRNAs as Promising Tumor Biomarkers
2014microRNAs (miRNAs) are small, nonprotein-coding RNAs that function as posttranscriptional regulators of target genes. miRNAs are involved in multiple cell differentiation, proliferation, and apoptosis processes that are closely related to tumorigenesis.
Meng, Chen +2 more
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Magyar onkologia, 2013
In the past decade the revolutionary development of molecular technology contributed a lot to the increase of our knowledge on cancer. These informations led to the discovery and understanding of those key regulatory changes in the genesis and progression of malignancies that can serve as targets in tumor diagnostics and therapy.
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In the past decade the revolutionary development of molecular technology contributed a lot to the increase of our knowledge on cancer. These informations led to the discovery and understanding of those key regulatory changes in the genesis and progression of malignancies that can serve as targets in tumor diagnostics and therapy.
openaire +1 more source