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Tumor biomarkers: PSA and beyond
Clinical Chemistry and Laboratory Medicine (CCLM), 2012Laboratory medicine plays an increasingly important role in the management of cancer patients (1, 2) . In none of the tumors has the advent of biomarkers changed the treatment in a more fundamental way than the introduction of prostate specifi c antigen (PSA) which has virtually transformed the management of prostate cancer.
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MicroRNAs as Biomarkers in Pituitary Tumors
Neurosurgery, 2014The use of extracellular microRNAs (miRNAs) as circulating biomarkers is currently leading to relevant advances in the diagnosis and assessment of prognosis of several diseases. Specific miRNAs have also been shown to play a role in the pathophysiology of many neoplastic and non-neoplastic diseases.
Antonio, Di Ieva +8 more
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Biomarkers in Gynecologic Tumors
2022Gynecologic malignancies are one of the most frequent cancers amongst women. Biomarkers are crucial for the differential diagnosis of adnexal masses; however, their potential for diagnosis is limited. In the era of difficulty in ovarian cancer screening, novel biomarkers are defined, but CA125 still remains the most valuable one. Circulating tumor DNAs,
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Potential Biomarkers in Metastatic Gastrointestinal Stromal Tumors
Clinical Cancer Research, 2007To the Editor: We read with great interest the article by Norden-Zfoni and colleagues in the May issue of Clinical Cancer Research . In this article, the investigators aimed to identify potential biomarkers in the blood of patients with metastatic gastrointestinal stromal tumors treated ...
Strijbos, Michiel +3 more
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Circulating microRNAs as Promising Tumor Biomarkers
2014microRNAs (miRNAs) are small, nonprotein-coding RNAs that function as posttranscriptional regulators of target genes. miRNAs are involved in multiple cell differentiation, proliferation, and apoptosis processes that are closely related to tumorigenesis.
Meng, Chen +2 more
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Biomarkers in Pancreatic Neuroendocrine Tumors
2014The aim of biomarkers is to identify patients most likely to benefit from a therapeutic strategy. Pancreatic neuroendocrine tumors are rare neoplasms that arise in the endocrine tissues of the pancreas. Pancreatic neuroendocrine tumors represent 3% of primary pancreatic neoplasms and their incidence has risen.
Theochari, Maria Serafeim +2 more
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Exosomal Hsp60: A Tumor Biomarker?
2019Exosomes (EXs) are extracellular vesicles containing proteins, DNA, mRNA, non-coding RNAs, such as miRNAs, and lipid. The EXs can be easily isolated from different biological fluids and their content is considered a potential biomarker in various diseases, such as cancer.
Stefano Fais +3 more
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Magyar onkologia, 2013
In the past decade the revolutionary development of molecular technology contributed a lot to the increase of our knowledge on cancer. These informations led to the discovery and understanding of those key regulatory changes in the genesis and progression of malignancies that can serve as targets in tumor diagnostics and therapy.
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In the past decade the revolutionary development of molecular technology contributed a lot to the increase of our knowledge on cancer. These informations led to the discovery and understanding of those key regulatory changes in the genesis and progression of malignancies that can serve as targets in tumor diagnostics and therapy.
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Brain and other central nervous system tumor statistics, 2021
Ca-A Cancer Journal for Clinicians, 2021Kimberly D Miller +2 more
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Antibody–drug conjugates: Smart chemotherapy delivery across tumor histologies
Ca-A Cancer Journal for Clinicians, 2022Paolo Tarantino +2 more
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