Results 51 to 60 of about 4,176,355 (337)

Tumor stiffness measured by shear wave elastography correlates with tumor hypoxia as well as histologic biomarkers in breast cancer

Cancer Imaging, 2020
Background Shear wave elastography (SWE) is an ultrasound technique for the noninvasive quantification of tissue stiffness. The hypoxic tumor microenvironment promotes tumor stiffness and is associated with poor prognosis in cancer.
Joonghyun Yoo, B. Seo, E. Park, Myoungae Kwon, Hoiseon Jeong, K. Cho, O. Woo, S. Song, J. Cha   +8 more
semanticscholar   +1 more source

Electrochemical Biosensors for Determination of Colorectal Tumor Biomarkers

Micromachines, 2020
The accurate determination of specific tumor markers associated with cancer with non-invasive or minimally invasive procedures is the most promising approach to improve the long-term survival of cancer patients and fight against the high incidence and ...
Jennifer Quinchia, Danilo Echeverri, A. Cruz-Pacheco, M. Maldonado, J. Orozco   +4 more
semanticscholar   +1 more source

Tumor-agnostic biomarkers

Practical oncology, 2021
A huge amount of data obtained during last 30 years in multiple translational works allowed both to break particular tumor types into subgroups based on molecular markers but also to create pan-tumor subgroups based on particular markers. These evidence suggest the new approach to diagnostic and treatment algorithms should be implemented.
openaire   +1 more source

Visualization of tumor heterogeneity and prediction of isocitrate dehydrogenase mutation status for human gliomas using multiparametric physiologic and metabolic MRI

Scientific Reports, 2022
This study aimed to differentiate isocitrate dehydrogenase (IDH) mutation status with the voxel-wise clustering method of multiparametric magnetic resonance imaging (MRI) and to discover biological underpinnings of the clusters.
Akifumi Hagiwara, Hiroyuki Tatekawa, Jingwen Yao, Catalina Raymond, Richard Everson, Kunal Patel, Sergey Mareninov, William H. Yong, Noriko Salamon, Whitney B. Pope, Phioanh L. Nghiemphu, Linda M. Liau, Timothy F. Cloughesy, Benjamin M. Ellingson   +13 more
doaj   +1 more source

Hepatocellular carcinoma: Review of disease and tumor biomarkers. [PDF]

, 2016
© The Author(s) 2016.Hepatocellular carcinoma (HCC) is a common malignancy and now the second commonest global cause of cancer death. HCC tumorigenesis is relatively silent and patients experience late symptomatic presentation. As the option for curative
Cox, IJ, Crossey, MM, Fye, HK, Gomez-Romero, M, Holmes, E, Kim, JU, Njie, R, Shariff, MI, Taylor-Robinson, SD   +8 more
core   +1 more source

Tumor-Cell–Macrophage Fusion Cells as Liquid Biomarkers and Tumor Enhancers in Cancer

International Journal of Molecular Sciences, 2020
Although molecular mechanisms driving tumor progression have been extensively studied, the biological nature of the various populations of circulating tumor cells (CTCs) within the blood is still not well understood.
Y. Manjunath, David Porciani, Jonathan B. Mitchem, K. Suvilesh, Diego M. Avella, E. Kimchi, K. Staveley-O’Carroll, D. H. Burke, Guangfu Li, J. Kaifi   +9 more
semanticscholar   +1 more source

Prognostic and predictive value of circulating tumor cells and CXCR4 expression as biomarkers for a CXCR4 peptide antagonist in combination with carboplatin-etoposide in small cell lung cancer: exploratory analysis of a phase II study. [PDF]

, 2017
Background Circulating tumor cells (CTCs) and chemokine (C-X-C motif) receptor 4 (CXCR4) expression in CTCs and tumor tissue were evaluated as prognostic or predictive markers of CXCR4 peptide antagonist LY2510924 plus carboplatin-etoposide (CE) versus ...
Baeten, Kurt, Connelly, Mark C, D'Haese, David, Flynt, Amy, Gross, Steve, McCleod, Michael, Morano, Carrie, Peek, Victoria L, Polzer, John, Raddad, Eyas, Repollet, Madeline, Roberson, Stephanie, Salgia, Ravi, Sanders, Renouard, Spigel, David R, Stille, John R, Um, Suzane L, Weaver, R Waide, Wijayawardana, Sameera R, Yan, S Betty   +19 more
core   +1 more source

Epigenetically inactivated RASSF1A as a tumor biomarker

Bosnian Journal of Basic Medical Sciences, 2020
RASSF1A represents one of the eight isoforms of the RASSF1 gene. RASSF1A is a tumor suppressor gene whose inactivation influences tumor initiation and development. In cancer, RASSF1A is frequently inactivated by mutations, loss of heterozygosity and, most commonly, by promoter hypermethylation.
Dora Raos, Monika Ulamec, Ana Katusic Bojanac, Floriana Bulic-Jakus, Davor Jezek, Nino Sincic   +5 more
openaire   +7 more sources

Dissecting the Role of AXL in Cancer Immune Escape and Resistance to Immune Checkpoint Inhibition

Frontiers in Immunology, 2022
The development and implementation of Immune Checkpoint Inhibitors (ICI) in clinical oncology have significantly improved the survival of a subset of cancer patients with metastatic disease previously considered uniformly lethal.
Agnete S. T. Engelsen, Maria L. Lotsberg, Raefa Abou Khouzam, Jean-Paul Thiery, Jean-Paul Thiery, Jean-Paul Thiery, James B. Lorens, Salem Chouaib, Salem Chouaib, Salem Chouaib, Salem Chouaib, Stéphane Terry, Stéphane Terry, Stéphane Terry, Stéphane Terry   +14 more
doaj   +1 more source

Tumor biomarkers for diagnosis, prognosis and targeted therapy

Signal Transduction and Targeted Therapy
Tumor biomarkers, the substances which are produced by tumors or the body’s responses to tumors during tumorigenesis and progression, have been demonstrated to possess critical and encouraging value in screening and early diagnosis, prognosis prediction,
Yuee Zhou, Lei Tao, Jia-Hui Qiu, Jing Xu, Xinyu Yang, Yu Zhang, Xinyu Tian, Xinqi Guan, X. Cen, Yinglan Zhao   +9 more
semanticscholar   +1 more source