ATP Citrate Lyase in Metabolic Disease: Mechanistic Insights and Clinical Potential
ATP citrate lyase (ACLY) is a central metabolic hub that diverts mitochondrial citrate to fuel de novo lipogenesis, cholesterol biosynthesis, and protein acetylation. Given its robust correlation with pathological changes in multiple human diseases, ACLY inhibitors featuring distinct pharmacological strengths have been developed for therapeutic ...
Wenbiao Wang +5 more
wiley +1 more source
Water Regime Determines Dose-Dependent Growth and Biomass Allocation Responses of Soybean Seedlings to <i>Bacillus subtilis</i> and <i>Bacillus amyloliquefaciens</i>. [PDF]
da Silva JPA +9 more
europepmc +1 more source
ABSTRACT Agricultural water management (AWM) is increasingly transitioning towards transformative thinking, where interconnected sectors, including water, energy and food, are managed holistically. Trends point towards cross‐sectoral and harmonised strategies to optimise water use efficiency and productivity, integrate renewable energy, promote ...
Luxon Nhamo +5 more
wiley +1 more source
Global patterns of C<sub>3</sub>/C<sub>4</sub> grass biomass allocation: how aridity mediates nitrogen-induced divergent strategies. [PDF]
Hu M +6 more
europepmc +1 more source
ABSTRACT This invited paper gives an overview of the challenges the world is facing and offers a possible solution for water and food security within the holistic integrated concept of the water–energy–food (WEF) nexus. The paper summarizes the experience the author gained through working on various research projects at national and international ...
Ragab Ragab
wiley +1 more source
Diversity of root system architecture and root-shoot biomass allocation in industrial hemp (Cannabis sativa L.). [PDF]
Morales EY +7 more
europepmc +1 more source
ABSTRACT Crop modelling is essential for agricultural water management but often relies on simplified water balance routines that limit representation of soil moisture dynamics. To address this limitation, we developed a coupled model that integrates the 1‐D Richards equation, solved using a finite difference method into the FAO AquaCrop.
Krishna Panthi +2 more
wiley +1 more source
Regulatory Effects of Paclobutrazol and Uniconazole Mixture on the Morphology and Biomass Allocation of <i>Amorpha fruticosa</i> Seedlings. [PDF]
Zhang J +7 more
europepmc +1 more source
ABSTRACT A recent UN report describes many regions as facing ‘water bankruptcy,’ a condition in which available water resources can no longer meet existing demands. In practice, this means irrigation will likely bear the greatest burden of future water‐use reductions, a complicated and fraught decision to make given its critical role in food security ...
Wim G. M. Bastiaanssen +30 more
wiley +1 more source
Rootstock genotype shapes whole-plant 3-D architecture and biomass allocation in field-grown grapevines. [PDF]
Fichtl L, Steng K, Schnepf A, Friedel M.
europepmc +1 more source

