Results 41 to 50 of about 51,684 (284)

Targeted decrease of portal hepatic pressure gradient improves ascites control after TIPS

Hepatology, EarlyView., 2022
The river diagram demonstrates that after transjugular intrahepatic portosystemic shunt insertion (TIPS) the majority of patients without ascites and 50% of the patients with ascites detectable at ultrasound, show the best response in the long term follow‐up.
Alexander Queck, Louise Schwierz, Wenyi Gu, Philip G. Ferstl, Christian Jansen, Frank E. Uschner, Michael Praktiknjo, Johannes Chang, Maximilian J. Brol, Filippo Schepis, Manuela Merli, Christian P. Strassburg, Jennifer Lehmann, Carsten Meyer, Jonel Trebicka   +14 more
wiley   +1 more source

Comparative and pharmacological investigation of bEVs from eight Lactobacillales strains

Scientific Reports
Bacterial extracellular vesicles (bEVs) have therapeutic potential by mimicking the effects of the microbiome. Here, we characterized bEVs from eight gram-positive Lactobacillales strains, evaluating their therapeutic potential.
Seoah Park, Jongsoo Mok, Hye-Min Yu, Hye-Jin An, Ga-Hyun Choi, Yeon-Seon Lee, Ki-Jin Kwon, Sung-Jun Choi, Kyung-Hee Kim, Soo-Jin Kim, Joonghoon Park   +10 more
doaj   +1 more source

An Overview of the BIOMed Project

, 2017
The purpose is to: 1) foster the national BioMedical Informatics (BMI) foundation aligning with the international medical informatics association (IMIA) in order to remodel the national strategies; 2) structure the BMHI strategic plans in Egypt and Jordan as models for other Arab States; 3) define the requirements for new joint EU-Mediterranean BMHI ...
John Mantas, Mohamed A. Wageih
openaire   +4 more sources

CAR‐Engineered Cell Therapies Beyond Cancer: Reprogramming Fibrosis and Immune‐Mediated Inflammation

Advanced Science, EarlyView.
CAR‐engineered cell therapies are expanding beyond cancer toward immune resetting, pathological‐cell clearance, matrix remodeling, and microenvironmental reprogramming in autoimmune, inflammatory, and fibrotic diseases. This Review compares CAR‐T, CAR‐macrophage, and CAR‐NK platforms and proposes controllable spatiotemporal reprogramming to align ...
Peng Jun Xu, Zhou Jing Zhang, Jing Jin, Hai Yuan Xu, Ya Xin Gu, Qian Qian Yang, You Lang Zhou   +6 more
wiley   +1 more source

The last continuous grasslands on Earth: Identification and conservation importance

Conservation Science and Practice, 2022
Grasslands are the most threatened and least protected biome. Yet, no study has been conducted to identify the last remaining continuous grasslands on Earth. Here, we used World Wildlife Fund (WWF) and International Union for Conservation of Nature (IUCN)
Rheinhardt Scholtz, Dirac Twidwell
doaj   +1 more source

Deforestation and Efficiency: Insights From Forest Transition in the Brazilian Cerrado

Agribusiness, EarlyView.
ABSTRACT This paper estimates technical efficiency (TE) and environmental efficiency (EE) of agricultural production at the municipal level of the Brazilian Cerrado in 2006 and 2017, and investigates their underlying mechanisms in relation to forest transition theory.
Ricardo Muniz Simões, Cassiano Bragagnolo, Humberto Francisco Silva Spolador   +2 more
wiley   +1 more source

From Vineyard Soil to Wine Fermentation: Microbiome Approximations to Explain the “terroir” Concept

Frontiers in Microbiology, 2017
Wine originally emerged as a serendipitous mix of chemistry and biology, where microorganisms played a decisive role. From these ancient fermentations to the current monitored industrial processes, winegrowers and winemakers have been continuously ...
Ignacio Belda, Ignacio Belda, Iratxe Zarraonaindia, Iratxe Zarraonaindia, Matthew Perisin, Antonio Palacios, Antonio Palacios, Alberto Acedo   +7 more
doaj   +1 more source

AS‐pHopt: An Optimal pH Prediction Model Enhanced by Active Site of Enzymes

Advanced Intelligent Discovery, EarlyView.
To address the low accuracy of enzyme optimal pH (pHopt) prediction, this study develops active site‐based pHopt (AS‐pHopt), a prediction model enhanced by active site information and pseudo‐label prediction. Integrating key structural and physicochemical features affecting enzyme pHopt, AS‐pHopt uses Evolutionary Scale Modeling (ESM)‐2 with active ...
Wenxiang Song, Xinmin Li, Hongbo Yu, Le Xiong, Guixia Liu, Weihua Li, Yun Tang   +6 more
wiley   +1 more source

Reverse Engineering of the Pediatric Sepsis Regulatory Network and Identification of Master Regulators

Biomedicines, 2021
Sepsis remains a leading cause of death in ICUs all over the world, with pediatric sepsis accounting for a high percentage of mortality in pediatric ICUs.
Raffael Azevedo de Carvalho Oliveira, Danilo Oliveira Imparato, Vítor Gabriel Saldanha Fernandes, João Vitor Ferreira Cavalcante, Ricardo D’Oliveira Albanus, Rodrigo Juliani Siqueira Dalmolin   +5 more
doaj   +1 more source

Exposure to heat waves and drought improves subsequent leaf heat tolerance for five oak species in southern California

American Journal of Botany, EarlyView.
Abstract Premise Given the threats of climate change, we investigated the impact of high temperatures separately and in combination with reduced soil water on leaf heat tolerance for five oaks (Fagaceae) with overlapping ranges in southern California, USA: Quercus agrifolia and Q. chrysolepis (evergreen species), Q. douglasii and Q.
Casey D. Wisely, G. Olivia Plumb, Mira N. Ranganath, Emily Dolida, Ishan Ashford, Graham Luethe, Tim Thibault, Gretchen B. North   +7 more
wiley   +1 more source