Results 141 to 150 of about 420,611 (253)
Advanced Science, EarlyView.FAK orchestrates a mechanical barrier limiting nanomedicine accumulation in solid tumors by coupling ECM remodeling with cytoskeletal tension. Genetic or pharmacological FAK inhibition dismantles this barrier, enhances clathrin‐mediated uptake and penetration, and overcomes delivery limitations to improve antitumor efficacy.
Tian Zhao +11 more
wiley +1 more source
Advanced Science, EarlyView.RCI is associated with functional suppression of oxytocinergic neurons in the PVN. Reduced PVNOXT neuronal activity contributes to altered sympathetic regulation involving the IML–sympathetic chain pathway, accompanied by changes in norepinephrine signaling at the BTI.
Liyang Wan +8 more
wiley +1 more source
Biomechanical Analysis of Elite Race Walking [PDF]
The aim of this study was to provide a comprehensive analysis of key biomechanical variables in race walking through the analysis of elite athletes in both competitive and laboratory settings.
Hanley, B
core +1 more source
Advanced Science, EarlyView.A self‐sustainable vehicular vibration and indoor environment monitoring IoT platform is developed which integrates a hybrid spring‐coupled broadband energy harvester with a machine learning‐assisted PAN‐CuSCN nanofiber triboelectric vibration sensor for subtle‐to‐wide‐range vibration detection and road/speed classification.
Trilochan Bhatta +6 more
wiley +1 more source
Advanced Science, EarlyView.This review presents a pathology‐driven framework unifying nanomedicine across TBI, SCI, and PNI. Epidemiological evidence and comparative single‐cell transcriptomic reanalysis define shared pathological modules, injury‐specific effectors, and therapeutic bottlenecks. Six functional paradigms connect nanomaterial structure and biological fate to injury‐
Mouyuan Sun +12 more
wiley +1 more source
Advanced Science, EarlyView.Mitochondrial quality control (MQC) collapse redefines osteoarthritis, intervertebral disc degeneration, and osteoporosis as disorders of organelle dysfunction. Damaged mitochondria leak mtDNA and metabolites, driving cGAS‐STING inflammation, epigenetic reprogramming, and metabolic memory.
Haiyang Gao +7 more
wiley +1 more source
Advanced Science, EarlyView.Concept of the MagGami‐based joint‐space haptic glove. a) Comparison between Cartesian‐space fingertip force feedback and distributed joint‐space torque feedback, highlighting the limitations of representative motor‐driven, pneumatic, and smart material‐based haptic actuators.
Tianhao Jin +9 more
wiley +1 more source
Power-Based Running Durability in Trained Runners: Preliminary Evidence of Speed-Adjusted Mechanical Drift as a Marker of Fatigue. [PDF]
Eur J Sport SciCartón-Llorente A +2 more
europepmc +1 more source
Biomechanical Properties of Bone and Biomechanics of Age - Related Fractures - Review
, 2007 From a biomechanical viewpoint, fractures are due to a structural failure of the bone. This failure occurs when the forces applied to the bone exceed its load – bearing capacity.
Rezzan Günaydın +1 more
core
Advanced Science, EarlyView.Fuyuan Huoxue decoction improves lumbar interbody fusion in rats while reducing inflammatory macrophage activity and supporting bone‐forming stem cells. Experiments implicate extracellular DNA and TLR9/NF‐κB signaling in early responses. These findings point to coordinated control of inflammation and osteogenesis as a potential route to stronger spinal
Hongwei Gao +8 more
wiley +1 more source