Results 161 to 170 of about 420,611 (253)

PHGDH‐Mediated Serine Metabolism in Nucleus Pulposus Cells Is a Potential Therapeutic Target for Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
When nucleus pulposus cells senesce, PHGDH decreases, reducing serine synthesis and glutathione, impairing antioxidant capacity. The intermediate α‐KG also drops, lowering JMJD3 demethylase activity, increasing H3K27me3 at the Rap1b promoter, and reducing Rap1b expression, whose down‐regulation in turn activates mTORC1 and suppresses autophagy ...
Hao‐Wei Xu   +5 more
wiley   +1 more source

Bridging Performance and Fate: A Framework for Sustainable, Composite‐Based Flexible Electronic Systems

open access: yesAdvanced Electronic Materials, EarlyView.
Composite‐based flexible electronics integrate biodegradable polymers, conductive networks, and multilayer device architectures to balance electrical performance, mechanical durability, and controlled degradation. Interfacial engineering and encapsulation regulate transport stability and operational lifetime, while programmed disassembly enables ...
Sayam, Sangho Cho
wiley   +1 more source

Acute Disc Herniation at the Proximal Junctional Segment (UIV/UIV + 1) Following Long Segment Spinal Fusion With Cement-Augmented Instrumentation: A Retrospective Study. [PDF]

open access: yesInt J Spine Surg
Saleh D   +11 more
europepmc   +1 more source

Clinical utility of pharyngeal high‐resolution manometry with impedance for upper esophageal sphincter dysfunction in gastroenterology

open access: yesAdvances in Digestive Medicine, EarlyView.
Abstract Pharyngeal high‐resolution manometry with impedance (P‐HRM‐I) is an established assessment method used to evaluate pharyngeal swallowing. It provides precise quantification of swallowing biomechanics that enable the detection of alterations in swallowing physiology.
Mistyka Schar   +5 more
wiley   +1 more source

Smart Bioinspired Material‐Based Actuators: Current Challenges and Prospects

open access: yesAdvanced Intelligent Systems, Volume 7, Issue 3, March 2025.
This work gathers, in a review style, an extensive and comprehensive literature overview on the development of autonomous actuators based on synthetic materials, bringing together valuable knowledge from several studies. Furthermore, the article identifies the fundamental principles of actuation mechanisms and defines key parameters to address the size
Alejandro Palacios   +4 more
wiley   +1 more source

Skin‐Conformal Myography for Real‐Time Hand Tracking Using a Laser‐Induced Graphene Strain Sensor Array

open access: yesAdvanced Intelligent Systems, Volume 7, Issue 3, March 2025.
A skin‐conformal wearable device based on laser‐induced graphene is developed for continuous strain measurement across the circumference of the forearm for gesture recognition and hand‐tracking applications. Post material optimization, the strain sensor array is integrated with a wearable wireless readout circuit for real‐time control of a robotic arm,
Vinay Kammarchedu   +2 more
wiley   +1 more source

Fatigue‐Driven Adaptive Assistance for a Semi‐Active Upper‐Limb Occupational Exoskeleton

open access: yesAdvanced Intelligent Systems, EarlyView.
Physical fatigue during a physical activity is estimated in real time to enable adaptive exoskeleton assistance. By continuously adjusting the level of support according to the user’s fatigue, this approach reduces physical demand and provides a pathway toward personalized exoskeleton assistance.
Seemab Zakir   +6 more
wiley   +1 more source

Sports Activity Recognition Using Textile‐Based Sensor Fusion and Complex‐Valued Residual Convolutional Neural Networks

open access: yesAdvanced Intelligent Systems, EarlyView.
Motion artifacts in electrocardiographic signals, conventionally dismissed as noise, are shown to encode discriminative activity information. A smart t‐shirt fusing textile strain sensors with textile ECG electrodes, processed through a complex‐valued residual network, recognizes 12 sport activities.
Nada Al‐azzawi   +4 more
wiley   +1 more source

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