Results 61 to 70 of about 2,917,391 (330)

Microwave imaging techniques for biomedical applications [PDF]

, 1999
Microwaves have been considered for medical applications involving the detection of organ movements and changes in tissue water content. More particularly cardiopulmonary interrogation via microwaves has resulted in various sensors monitoring ventricular
Bolomey, Jean Charles, Broquetas Ibars, Antoni, Geffrin, J M, Joachimowicz, N, Jofre Roca, Lluís, Joisel, A, Mallorquí Franquet, Jordi Joan, Vall-Llossera Ferran, Mercedes Magdalena, Vall·Llossera, M   +8 more
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

WormBase 2007 [PDF]

, 2008
WormBase (www.wormbase.org) is the major publicly available database of information about Caenorhabditis elegans, an important system for basic biological and biomedical research. Derived from the initial ACeDB database of C. elegans genetic and sequence
A. Petcherski, A. Rogers, Ashburner, C. Bastiani, C. Nakamura, D. Blasiar, D. Wang, Deplancke, E. M. Schwarz, G. Schindelman, G. Williams, H.-M. Muller, Hillier, Husson, I. Antoshechkin, J. Chan, J. Fernandes, J. Spieth, K. Van Auken, K. Yook, Kirienko, L. D. Stein, Li, Li, M. A. Tuli, M. Han, Matera, Meyer, M  ller, O'Brien, P. Canaran, P. Davis, P. Ozersky, P. W. Sternberg, Potter, R. Durbin, R. Kishore, R. Lee, Ruby, S. McKay, T. Bieri, T. J. Fiedler, T. W. Harris, Tatusov, W. J. Chen, W. Spooner, Wachi, Walhout, X. Wang, Zemann, Zhang, Zhong   +51 more
core   +3 more sources

Preparing historically underrepresented trainees for biomedical cancer research careers at Huntsman Cancer Institute/University of Utah Health [PDF]

, 2021
Ana Mariá López, José E. Rodríguez, Kathryn Browning Hawes, Anna Marsden, Don Ayer, Donna Ziegenfuss, Kola Okuyemi   +6 more
openalex   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Tailoring the mechanical and degradation properties of 3DP PLA/PCL scaffolds for biomedical applications

Reviews on Advanced Materials Science
In the realms of tissue engineering and 3D printing, tailoring scaffold mechanical characteristics and degradation rates is crucial for superior performance in a range of biomedical settings.
Kalva Sumama Nuthana, Zakaria Yahya, Velasquez Carlos A., Koç Muammer   +3 more
doaj   +1 more source

Suggestive Annotation: A Deep Active Learning Framework for Biomedical Image Segmentation

, 2017
Image segmentation is a fundamental problem in biomedical image analysis. Recent advances in deep learning have achieved promising results on many biomedical image segmentation benchmarks.
B Efron, B Settles, K Sirinukunwattana, O Ronneberger, U Feige, Y Xu   +5 more
core   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Remotely-actuated biomedical switch [PDF]

, 1969
Remotely-actuated biomedical switching circuit using transistors consumes no power in the off position and can be actuated by a single-frequency telemetry pulse to control implanted instrumentation. Silicon controlled rectifiers permit the circuit design
Lee, R. D.
core   +1 more source

This before That: Causal Precedence in the Biomedical Domain

, 2016
Causal precedence between biochemical interactions is crucial in the biomedical domain, because it transforms collections of individual interactions, e.g., bindings and phosphorylations, into the causal mechanisms needed to inform meaningful search and ...
Bell, Dane, Hahn-Powell, Gus, Surdeanu, Mihai, Valenzuela-Escárcega, Marco A.   +3 more
core   +1 more source