Results 91 to 100 of about 7,364,821 (307)

Respiratory motion-compensated high-resolution 3D whole-heart T1ρ mapping

Journal of Cardiovascular Magnetic Resonance, 2020
Background Cardiovascular magnetic resonance (CMR) T1ρ mapping can be used to detect ischemic or non-ischemic cardiomyopathy without the need of exogenous contrast agents.
Haikun Qi, Aurelien Bustin, Thomas Kuestner, Reza Hajhosseiny, Gastao Cruz, Karl Kunze, Radhouene Neji, René M. Botnar, Claudia Prieto   +8 more
doaj   +1 more source

Recent Development of Inorganic Nanoparticles for Biomedical Imaging

ACS Central Science, 2018
Inorganic nanoparticle-based biomedical imaging probes have been studied extensively as a potential alternative to conventional molecular imaging probes.
Dokyoon Kim, Jonghoon Kim, Yong Il Park, N. Lee, T. Hyeon   +4 more
semanticscholar   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Offline reinforcement learning combining generalized advantage estimation and modality decomposition interaction

Scientific Reports
Transformers show great potential in offline reinforcement learning via trajectory sequence modeling for action prediction. However, existing Transformer-based methods face limitations, such as ineffective trajectory stitching and the neglect of deep ...
Kaixin Jin, Lifang Wang, Xiwen Wang, Wei Guo, Qiang Han, Xiaoqing Yu   +5 more
doaj   +1 more source

Imaging Active Infection in vivo Using D-Amino Acid Derived PET Radiotracers

Scientific Reports, 2017
Occult bacterial infections represent a worldwide health problem. Differentiating active bacterial infection from sterile inflammation can be difficult using current imaging tools. Present clinically viable methodologies either detect morphologic changes
Kiel D. Neumann, Javier E. Villanueva-Meyer, Christopher A. Mutch, Robert R. Flavell, Joseph E. Blecha, Tiffany Kwak, Renuka Sriram, Henry F. VanBrocklin, Oren S. Rosenberg, Michael A. Ohliger, David M. Wilson   +10 more
doaj   +1 more source

FeSe quantum dots for in vivo multiphoton biomedical imaging

Science Advances, 2019
FeSe quantum dots of multiphoton absorption were used to image tumor cells in deeper tissue. An immense demand in biomedical imaging is to develop efficient photoluminescent probes with high biocompatibility and quantum yield, as well as multiphoton ...
J. Kwon, S. Jun, S. Choi, X. Mao, Jeonghyo Kim, E. Koh, Yong-Hoon Kim, S. Kim, D. Hwang, Choongrak Kim, Jaebeom Lee   +10 more
semanticscholar   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

In vivo 3D myocardial membrane potential mapping in humans using PET/MRI

EJNMMI Research
Background The mitochondrial membrane potential is a key biophysical parameter of mitochondrial function, which can be useful for the diagnosis and treatment monitoring of various cardiac diseases.
Felicitas J. Bijari, Paul Kyu Han, Thibault Marin, Wonil Lee, Yanis Chemli, Inna Gertsenshteyn, Ismaël B. G. Mounime, Yanis Djebra, Didi Chi, Marc D. Normandin, Chao Ma, Georges El Fakhri   +11 more
doaj   +1 more source

Building open lab hardware to tackle antimicrobial resistance [PDF]

Microbiological imaging can be lengthy and labour-intensive without expensive lab-automation. Using Open Source hardware and software, Dr Al Edwards’ Biomedical Technology Lab designed a robot to take high-resolution images of experiments capturing ...
Bull, Stephanie, Edwards, Al, Needs, Sarah   +2 more
core   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source