Results 61 to 70 of about 2,637,783 (288)

Computer Methods in Biomechanics and Biomedical Engineering: Imaging & Visualization

, 2013
Subject Classifications Applied Mathematics; Biomaterials; Biomaterials; Biomaterials & Medical Devices; Biomechanics; Biomechanics and Human Movement Science; Biomedical Engineering; Engineering & Technology; Fluid Mechanics; Materials Science ...
SGALLARI, FIORELLA
core   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Optimization of brain PET markerless head motion correction in a large human cohort

EJNMMI Physics
Purpose Uncorrected head motion in brain PET degrades image resolution and biases quantification. Previously, we evaluated the United Imaging Healthcare markerless motion tracking (UMT) system for brain PET (Baseline UMT). This study provides an expanded
Tianyi Zeng, Jiazhen Zhang, Jean-Dominique Gallezot, Kathryn Fontaine, Weize Jiang, Paul Gravel, Tim Mulnix, Mika Naganawa, Zhaohui Yang, Xinyue Zhang, Su Wang, Xishan Sun, Lingzhi Hu, Richard E. Carson   +13 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Virtual interaction and visualisation of 3D medical imaging data with VTK and Unity

Healthcare Technology Letters, 2018
The authors present a method to interconnect the Visualisation Toolkit (VTK) and Unity. This integration enables them to exploit the visualisation capabilities of VTK with Unity's widespread support of virtual, augmented, and mixed reality displays, and ...
Gavin Wheeler, Shujie Deng, Nicolas Toussaint, Kuberan Pushparajah, Julia A. Schnabel, John M. Simpson, Alberto Gomez   +6 more
doaj   +1 more source

Automatic segmentation of biomedical images [PDF]

ICASSP-88., International Conference on Acoustics, Speech, and Signal Processing, 2003
A new methodology which combines thresholding and probabilistic relaxation labelling process is proposed for automatic segmentation of biomedical electron micrograph images. The image is first thresholded and initial label probabilities of individual pixels are assigned according to the distance of each pixel to the clusters resulted from thresholding.
P. W. Fung, K. K. Ly, Yianni Attikiouzel
openaire   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Three-dimensional imaging and scanning: Current and future applications for pathology

Journal of Pathology Informatics, 2017
Imaging is vital for the assessment of physiologic and phenotypic details. In the past, biomedical imaging was heavily reliant on analog, low-throughput methods, which would produce two-dimensional images.
Navid Farahani, Alex Braun, Dylan Jutt, Todd Huffman, Nick Reder, Zheng Liu, Yukako Yagi, Liron Pantanowitz   +7 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source